Page last updated: 2024-12-08

beauverolides

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

beauverolides: beauverolides H & I have been encountered in our literature; cyclodepsopeptide from the entemopathogenic fungus Beauvaria bassiana Bals; RN given refers to beauverolide H [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID194155
MeSH IDM0061930

Synonyms (7)

Synonym
62995-90-8
beauverolides
cyclo-((r)-beta-hydroxynonanoyl-l-phenylalanyl-alanyl-d-leucyl)
beauverolide h
d-leucine, n-(n-(n-(3-hydroxy-1-oxononyl)-l-phenylalanyl)-l-alanyl)-, lambda-lactone, (r)-
9-benzyl-13-hexyl-5,8,11-trihydroxy-6-methyl-3-(2-methylpropyl)-1-oxa-4,7,10-triazacyclotrideca-4,7,10-trien-2-one
DTXSID10978882

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" We show that the fungal natural products beauveriolides I and III can potently decrease Abeta secretion from cells expressing human amyloid precursor protein; this offers a potential new scaffold for the development of compounds with proven bioavailability for the treatment of AD."( The natural products beauveriolide I and III: a new class of beta-amyloid-lowering compounds.
Boldt, GE; Chen, Y; Rogel, JK; Wentworth, P; Witter, DP, 2009
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (28)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (14.29)18.2507
2000's13 (46.43)29.6817
2010's8 (28.57)24.3611
2020's3 (10.71)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.40

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.40 (24.57)
Research Supply Index3.40 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.40)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.45%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other28 (96.55%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]