angelmarin: from Angelica pubescens, anti-cancer agent able to eliminate the tolerance of cancer cells to nutrient starvation; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Angelica | genus | A plant genus of the family Apiaceae.[MeSH] | Apiaceae | A large plant family in the order Apiales, also known as Umbelliferae. Most are aromatic herbs with alternate, feather-divided leaves that are sheathed at the base. The flowers often form a conspicuous flat-topped umbel. Each small individual flower is usually bisexual, with five sepals, five petals, and an enlarged disk at the base of the style. The fruits are ridged and are composed of two parts that split open at maturity.[MeSH] |
| Angelica pubescens | species | [no description available] | Apiaceae | A large plant family in the order Apiales, also known as Umbelliferae. Most are aromatic herbs with alternate, feather-divided leaves that are sheathed at the base. The flowers often form a conspicuous flat-topped umbel. Each small individual flower is usually bisexual, with five sepals, five petals, and an enlarged disk at the base of the style. The fruits are ridged and are composed of two parts that split open at maturity.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 71313386 |
| CHEMBL ID | 4126404 |
| MeSH ID | M0496318 |
| Synonym |
|---|
| angelmarin |
| CHEMBL4126404 |
| AKOS040734170 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1498662 | Cytotoxicity against human HepG2 cells at 10 uM | 2018 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 28, Issue:14 | Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells. |
| AID1498663 | Cytoprotective activity against 100 uM t-BHP-induced oxidative stress in human HepG2 cells assessed as cell viability preincubated for 1 hr followed by t-BHP addition measured after 3 hrs by CCK-8 assay (Rvb = 22%) | 2018 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 28, Issue:14 | Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (24.27) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||