Page last updated: 2024-12-06
3-oxauracil
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Description
3-Oxauracil, also known as uracil-6-one, is a heterocyclic compound related to uracil. It is a derivative of uracil with an additional carbonyl group at the 3-position. 3-Oxauracil has been studied for its potential biological activities, including its effects on DNA synthesis and its role in the formation of certain types of cancer. Its synthesis involves a multi-step process, and its effects are typically investigated in cell culture or animal models. Further research is needed to fully understand the role of 3-oxauracil in biological systems.'
3-oxauracil: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 73278 |
| CHEMBL ID | 3250627 |
| SCHEMBL ID | 288527 |
| MeSH ID | M0064635 |
Synonyms (25)
| Synonym |
|---|
| 3h-[1,3]oxazine-2,6-dione |
| 2h-1,3-oxazine-2,6(3h)-dione |
| 3h-1,3-oxazine-2,6-dione |
| nsc 163038 |
| brn 0112222 |
| 1,3-oxazine-2,6-dione |
| 2,3-dihydro-1,3-6h-oxazine-2,6-dione |
| nsc163038 |
| 3-oxauracil |
| 2h-1,6(3h)-dione |
| 34314-63-1 |
| nsc-163038 |
| AKOS004903244 |
| unii-14lw71vvm6 |
| 14lw71vvm6 , |
| 2-27-00-00295 (beilstein handbook reference) |
| CHEMBL3250627 |
| WQAIPNTUCFSZRZ-UHFFFAOYSA-N |
| SCHEMBL288527 |
| DTXSID30187878 |
| oxy-6h-1,3-oxazin-6-one |
| A912662 |
| FT-0725220 |
| 2,3-dihydro-6h-1,3-oxazine-2,6-dione |
| CS-0359236 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1136852 | Growth inhibition of mouse L1210 cells | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Synthesis and biological activity of 5-fluoro- and 5-methyl-1,3-oxazine-2,6(3H)-dione. |
| AID1136850 | Growth inhibition of Streptococcus faecium | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Synthesis and biological activity of 5-fluoro- and 5-methyl-1,3-oxazine-2,6(3H)-dione. |
| AID1136851 | Growth inhibition of Escherichia coli | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Synthesis and biological activity of 5-fluoro- and 5-methyl-1,3-oxazine-2,6(3H)-dione. |
| AID1136864 | Stability of the compound in synthetic growth medium assessed as compound remaining at 37 degC after 16 hrs | 1979 | Journal of medicinal chemistry, May, Volume: 22, Issue:5 | Synthesis and biological activity of 5-fluoro- and 5-methyl-1,3-oxazine-2,6(3H)-dione. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (11)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||