| Assay ID | Title | Year | Journal | Article |
|---|
| AID117798 | The effect on NADH oxidation in the presence of MPO-H2O2. | 1981 | Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
| Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. |
| AID96665 | Growth inhibitory activity against L1210 lymphocytic leukemia cells. | 1983 | Journal of medicinal chemistry, Oct, Volume: 26, Issue:10
| Autoxidation of the antitumor drug 9-hydroxyellipticine and its derivatives. |
| AID81867 | Inhibitory effect against HCT8 Human colon adenocarcinoma; inactive | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7
| Basically substituted ellipticine analogues as potential antitumor agents. |
| AID97904 | Compound was tested for its cytotoxic activity against murine leukemia L1210 cells in mice after intraperitoneal treatment, expressed as LD0 (highest nonlethal dose). | 1981 | Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
| Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. |
| AID54618 | Apparent binding constant (Kapp) for calf thymus DNA was measured by competition with ethidium bromide | 1984 | Journal of medicinal chemistry, Sep, Volume: 27, Issue:9
| Potential antitumor agents: synthesis and biological properties of aliphatic amino acid 9-hydroxyellipticinium derivatives. |
| AID96644 | Compound was tested for its antitumor activity against murine leukemia L1210 cells in vitro, expressed as ID50 | 1981 | Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
| Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. |
| AID96662 | Dose that reduces the L1210 leukemia cell growth in vitro by 50% after 48 hr as compared to controls | 1984 | Journal of medicinal chemistry, Sep, Volume: 27, Issue:9
| Potential antitumor agents: synthesis and biological properties of aliphatic amino acid 9-hydroxyellipticinium derivatives. |
| AID132189 | Percent Increase in life span (ILS) over controls (10e5 L1210 leukemia cells) at LD0/2 by ip administration of the drug into mouse (single injection 2 hr after cell grafting) | 1984 | Journal of medicinal chemistry, Sep, Volume: 27, Issue:9
| Potential antitumor agents: synthesis and biological properties of aliphatic amino acid 9-hydroxyellipticinium derivatives. |
| AID100465 | Inhibitory effect against L1210 leukemia in tissue culture | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7
| Basically substituted ellipticine analogues as potential antitumor agents. |
| AID117503 | he effect on oxygen consumed in the presence of MPO-H2O2. | 1981 | Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
| Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. |
| AID116287 | Increase in life span over controls (10e5 cells) in mice after intraperitoneal treatment of the compound. | 1981 | Journal of medicinal chemistry, Mar, Volume: 24, Issue:3
| Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. |
| AID134221 | Compound tested in vivo for highest nontoxic lethal dose administered intraperitoneally that reduces the L1210 leukemia cell growth | 1984 | Journal of medicinal chemistry, Sep, Volume: 27, Issue:9
| Potential antitumor agents: synthesis and biological properties of aliphatic amino acid 9-hydroxyellipticinium derivatives. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |