Compounds > 1,4-diazepane
Page last updated: 2024-11-06

1,4-diazepane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,4-diazepane: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID68163
SCHEMBL ID34142
MeSH IDM0541324

Synonyms (50)

Synonym
AC-4548
[1,4]diazepane
1,4-diazacycloheptane
homopiperazine
1h-1,4-diazepine, hexahydro-
brn 0102711
perhydro-1,4-diazepine
einecs 208-016-1
hexahydro-1,4-diazepine
trimethyleneethylenediamine
505-66-8
inchi=1/c5h12n2/c1-2-6-4-5-7-3-1/h6-7h,1-5h
homopiperazine, 98%
1,4-diazepane
FT-0660667
H0572
AKOS000119722
unii-95cl167w8t
5-23-03-00240 (beilstein handbook reference)
95cl167w8t ,
A828180
FT-0688601
FT-0600442
LF-0555
AM100887
hexahydro-1h-1,4-diazepine
SCHEMBL34142
homopiperzine
[1,4]-diazepane
1,4-diazepan
homopiperizine
[1.4]diazepan
hexahydro-2h-1,4-diazepine
perhydro-[1,4]-diazepine
DTXSID1060130
1,4-diazepane #
STR02277
Q-101030
homopiperazine;
mfcd00006933
CS-W007768
F0001-1316
2,3,4,5,6,7-hexahydro-1h-1,4-diazepine
homopiperazine, technical, >=98.0% (nt)
F10906
BCP15067
STL197515
129549-81-1
Q27271776
EN300-19058
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.00)29.6817
2010's18 (90.00)24.3611
2020's1 (5.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.34

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.34 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.34)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
milrinone
[no description available]		2.0510bipyridines;
nitrile;
pyridone		cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
piperazine
[no description available]		2.7630azacycloalkane;
piperazines;
saturated organic heteromonocyclic parent		anthelminthic drug
uridine
[no description available]		2.2110uridinesdrug metabolite;
fundamental metabolite;
human metabolite
molybdenum
Molybdenum: A metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.95. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase.		2.0610chromium group element atommicronutrient
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.		2.07101,2,3-triazole
levofloxacin
Levofloxacin: The L-isomer of Ofloxacin.. levofloxacin : An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase.		2.25109-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
ethylmorphine
Ethylmorphine: A narcotic analgesic and antitussive. It is metabolized in the liver by ETHYLMORPHINE-N-DEMETHYLASE and used as an indicator of liver function.		2.0810morphinane alkaloid
sulfur
Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.		2.0710chalcogen;
nonmetal atom		macronutrient
ConditionIndicatedRelationship StrengthStudiesTrials
E coli Infections
[description not available]		02.2510
Escherichia coli Infections
Infections with bacteria of the species ESCHERICHIA COLI.		02.2510
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		02.1510
Long Sleeper Syndrome
[description not available]		02.0510
Sleep Wake Disorders
Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.		02.0510
Cancer of Prostate
[description not available]		02.0610
Prostatic Neoplasms
Tumors or cancer of the PROSTATE.		02.0610
Allergic Reaction
[description not available]		02.0710
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.		02.0710
Hypersensitivity
Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.		02.0710