1,4-benzoquinoneimine profile

1,4-Benzoquinoneimine is a **highly reactive**, **unstable** organic compound with the molecular formula **C₆H₅NO**. It's not a commonly known or researched compound in itself, and there's limited information available about it.

**It is important to note that it is very likely that 1,4-benzoquinoneimine does not exist as a stable compound.** This is because the structure would be highly reactive due to the presence of a nitrogen atom directly bonded to a quinone ring. This combination would result in a highly unstable molecule, which is likely to quickly decompose or react with other molecules.

**Instead of 1,4-benzoquinoneimine, researchers often investigate related compounds:**

* **Benzoquinone** (C₆H₄O₂) is a well-studied compound with various applications in organic synthesis and medicinal chemistry.
* **Quinone imines** (also known as **iminoquinones**) are a class of compounds that contain a nitrogen atom bonded to a quinone ring. These compounds are often studied for their biological activity, such as their ability to act as inhibitors of enzymes or as antimicrobial agents.

**Therefore, while the specific compound 1,4-benzoquinoneimine may not be of significant research interest, the concept of quinone imines and their properties are relevant in various scientific fields.**

**If you are interested in specific research on quinone imines, it's advisable to search for information using the term quinone imine or iminoquinone in databases like PubMed or Google Scholar.** This will provide you with relevant articles on the synthesis, properties, and applications of these compounds.

ID Source	ID
PubMed CID	151062
CHEBI ID	50192
SCHEMBL ID	59611
MeSH ID	M0177157

Synonym
p-quinonimine
pbqi
2,5-cyclohexadien-1-one, 4-imino-
4-imino-2,5-cyclohexadien-1-one
1,4-benzoquinoneimine
brn 1851461
p-benzoquinone monoimine
p-benzoquinone imine
p-benzoquinonimine
1,4-benzoquinone imine
3009-34-5
4-iminocyclohexa-2,5-dien-1-one
CHEBI:50192
benzoquinone mono-imine
3-07-00-03365 (beilstein handbook reference)
5evq7k6t93 ,
unii-5evq7k6t93
SCHEMBL59611
benzoquinone imine
para-benzoquinone monoimine
Q27121974
DTXSID10952501
CS-0164216
4-iminocyclohexa-2,5-dienone? (sorafenib impurity pound(c)

Class	Description
quinone imine	An imine formed formally from a quinone by replacement of one or more atoms of quinonoid oxygen by =NH or =NR.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	4 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
4-aminophenol 4-aminophenol: RN given refers to parent cpd. 4-aminophenol : An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.	2.06	1	aminophenol	allergen; metabolite
diclofenac Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.. diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.	2.13	1	amino acid; aromatic amine; dichlorobenzene; monocarboxylic acid; secondary amino compound	antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
quinone benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.. 1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.. quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).	2.39	2	1,4-benzoquinones	cofactor; human xenobiotic metabolite; mouse metabolite
4-fluoroaniline 4-fluoroaniline: chemical intermediate manufactured by the Halex process; RN given refers to parent cpd; structure given in first source. 4-fluoroaniline : A primary arylamine that is the derivative of aniline in which the hydrogen at position 4 has been substituted by fluorine. It is used as an intermediate in the manufacture of pharmaceuticals, herbicides and plant growth regulators.	1.97	1	fluoroaniline; primary arylamine
2,3,4,5,6-pentafluoroaniline 2,3,4,5,6-pentafluoroaniline: structure given in first source	1.97	1
gold Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.	2.06	1	copper group element atom; elemental gold
n-acetyl-4-benzoquinoneimine N-acetyl-4-benzoquinoneimine: reactive arylating intermediate from acetaminophen & N-hydroxyacetaminophen; structure given in first source	1.97	1	ketoimine; quinone imine
biotin vitamin B7 : Any member of a group of vitamers that belong to the chemical structural class called biotins that exhibit biological activity against vitamin B7 deficiency. Vitamin B7 deficiency is very rare in individuals who take a normal balanced diet. Foods rich in biotin are egg yolk, liver, cereals, vegetables (spinach, mushrooms) and rice. Symptoms associated with vitamin B7 deficiency include thinning hair, scaly skin rashes around eyes, nose and mouth, and brittle nails. The vitamers include biotin and its ionized and salt forms.	2.06	1	biotins; vitamin B7	coenzyme; cofactor; Escherichia coli metabolite; fundamental metabolite; human metabolite; mouse metabolite; nutraceutical; prosthetic group; Saccharomyces cerevisiae metabolite
nadp [no description available]	1.97	1
sulfur Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.	2.06	1	chalcogen; nonmetal atom	macronutrient
nad NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.	2.06	1	organophosphate oxoanion	cofactor; human metabolite; hydrogen acceptor; Saccharomyces cerevisiae metabolite

Condition	Indicated	Relationship Strength	Studies	Trials
Acute Liver Injury, Drug-Induced [description not available]	0	2.13	1	0
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.	0	2.13	1	0

1,4-benzoquinoneimine

Cross-References

Synonyms (24)

Drug Classes (1)

Research

Studies (6)

Market Indicators

Research Demand Index: 12.38

Study Types