Page last updated: 2024-10-06

T-cell activation SARS-CoV-2

Proteins (92)

ProteinSynonymsTaxonomy
HLA class II histocompatibility antigen, DR beta 3 chainMHC class II antigen DRB3Homo sapiens (human)
Lymphocyte cytosolic protein 2SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76Homo sapiens (human)
Signal transducer and activator of transcription 4Homo sapiens (human)
Interleukin-17AIL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8Homo sapiens (human)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1EC 3.4.22.-; MALT lymphoma-associated translocation; ParacaspaseHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformPI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110deltaHomo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
Tyrosine-protein kinase JAK2EC 2.7.10.2; Janus kinase 2; JAK-2Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Tyrosine-protein kinase LckEC 2.7.10.2; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCKHomo sapiens (human)
Tyrosine-protein kinase FynEC 2.7.10.2; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-FynHomo sapiens (human)
G1/S-specific cyclin-D1B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogeneHomo sapiens (human)
NF-kappa-B inhibitor alphaI-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Non-receptor tyrosine-protein kinase TYK2EC 2.7.10.2Homo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 2MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2Homo sapiens (human)
Glycogen synthase kinase-3 betaGSK-3 beta; EC 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Transcription factor p65Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Homo sapiens (human)
Protein kinase C theta typeEC 2.7.11.13; nPKC-thetaHomo sapiens (human)
Bcl-2-like protein 1Bcl2-L-1; Apoptosis regulator Bcl-XHomo sapiens (human)
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoformEC 3.1.3.16; CAM-PRP catalytic subunit; Calcineurin, testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoformHomo sapiens (human)
Nuclear factor of activated T-cells, cytoplasmic 1 NF-ATc1; NFATc1; NFAT transcription complex cytosolic component; NF-ATc; NFATcHomo sapiens (human)
T-cell-specific surface glycoprotein CD28TP44Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Receptor-type tyrosine-protein phosphatase CEC 3.1.3.48; Leukocyte common antigen; L-CA; T200Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Tyrosine-protein kinase ZAP-70EC 2.7.10.2; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinaseHomo sapiens (human)
Growth factor receptor-bound protein 2Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2Homo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
Spike glycoproteinS glycoprotein; E2; Peplomer proteinSevere acute respiratory syndrome coronavirus 2
Interferon betaIFN-beta; Fibroblast interferonHomo sapiens (human)
DEP domain-containing mTOR-interacting proteinDEP domain-containing protein 6Homo sapiens (human)
Lymphotoxin-alphaLT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1Homo sapiens (human)
Forkhead box protein O3AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1Homo sapiens (human)
Linker for activation of T-cells family member 136 kDa phospho-tyrosine adapter protein; pp36; p36-38Homo sapiens (human)
HLA class II histocompatibility antigen, DRB1 beta chain Human leukocyte antigen DRB1; HLA-DRB1Homo sapiens (human)
Interferon alpha/beta receptor 1IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1Homo sapiens (human)
Nuclear factor NF-kappa-B p105 subunitDNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Homo sapiens (human)
Myeloid differentiation primary response protein MyD88Homo sapiens (human)
T-cell surface glycoprotein CD4T-cell surface antigen T4/Leu-3Homo sapiens (human)
Interleukin-23 subunit alphaIL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19Homo sapiens (human)
Inducible T-cell costimulatorActivation-inducible lymphocyte immunomediatory moleculeHomo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
NF-kappa-B essential modulatorNEMO; FIP-3; IkB kinase-associated protein 1; IKKAP1; Inhibitor of nuclear factor kappa-B kinase subunit gamma; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma; NF-kappa-B essential modifierHomo sapiens (human)
Interleukin-12 receptor subunit beta-1IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta componentHomo sapiens (human)
Cyclin-dependent kinase inhibitor 2ACyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4AHomo sapiens (human)
GTPase HRasEC 3.6.5.2; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21rasHomo sapiens (human)
Tumor necrosis factorCachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-aHomo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Rapamycin-insensitive companion of mTORAVO3 homolog; hAVO3Homo sapiens (human)
Regulatory-associated protein of mTORRaptor; p150 target of rapamycin (TOR)-scaffold proteinHomo sapiens (human)
Target of rapamycin complex subunit LST8TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8Homo sapiens (human)
RAS guanyl-releasing protein 1Calcium and DAG-regulated guanine nucleotide exchange factor II; CalDAG-GEFII; Ras guanyl-releasing proteinHomo sapiens (human)
Interferon gammaIFN-gamma; Immune interferonHomo sapiens (human)
Inositol 1,4,5-trisphosphate receptor type 1IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptorHomo sapiens (human)
Proto-oncogene c-FosCellular oncogene fos; G0/G1 switch regulatory protein 7Homo sapiens (human)
Interleukin-2IL-2; T-cell growth factor; TCGFHomo sapiens (human)
GTP-binding protein RhebRas homolog enriched in brainHomo sapiens (human)
Interleukin-23 receptorIL-23 receptor; IL-23RHomo sapiens (human)
Cytotoxic T-lymphocyte protein 4Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4Homo sapiens (human)
Interleukin-4IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; PitrakinraHomo sapiens (human)
C-C motif chemokine 28Mucosae-associated epithelial chemokine; MEC; Protein CCK1; Small-inducible cytokine A28Homo sapiens (human)
T-cell surface glycoprotein CD3 delta chainT-cell receptor T3 delta chainHomo sapiens (human)
T-lymphocyte activation antigen CD86Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1Homo sapiens (human)
C-C motif chemokine 19Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19Homo sapiens (human)
GRB2-related adapter protein 2Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter MonaHomo sapiens (human)
B-cell lymphoma/leukemia 10B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-contaiHomo sapiens (human)
HLA class II histocompatibility antigen, DR alpha chainMHC class II antigen DRAHomo sapiens (human)
T-cell surface glycoprotein CD3 epsilon chainT-cell surface antigen T3/Leu-4 epsilon chainHomo sapiens (human)
T-cell surface glycoprotein CD3 gamma chainT-cell receptor T3 gamma chainHomo sapiens (human)
T cell receptor alpha chain MC.7.G5MC.7.G5 TRA; TR alpha chain TRAV38-2DV8*01J31*01C*01Homo sapiens (human)
T cell receptor beta chain MC.7.G5TR beta chain TRBV25-1*01J2S3*01C2*01; MC.7.G5 TRBHomo sapiens (human)
T-cell surface glycoprotein CD3 zeta chainT-cell receptor T3 zeta chainHomo sapiens (human)
Interleukin-12 subunit alphaIL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell stimulatory factor chain 1; NKSF1Homo sapiens (human)
Interleukin-12 subunit betaIL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2Homo sapiens (human)
T-lymphocyte activation antigen CD80Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7Homo sapiens (human)
Interferon alpha/beta receptor 2IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2; Interferon alpha binding protein; Type I interferon receptor 2Homo sapiens (human)
TuberinTuberous sclerosis 2 proteinHomo sapiens (human)
Interleukin-18 receptor 1IL-18R-1; IL-18R1; EC 3.2.2.6; CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; Interleukin-18 receptor alpha; IL-18R-alpha; IL-18RalphaHomo sapiens (human)
HamartinTuberous sclerosis 1 proteinHomo sapiens (human)
Interleukin-12 receptor subunit beta-2IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2Homo sapiens (human)
Caspase recruitment domain-containing protein 11CARD-containing MAGUK protein 1; Carma 1Homo sapiens (human)
Probable E3 ubiquitin-protein ligase IRF2BPLEC 2.3.2.27; Enhanced at puberty protein 1; Interferon regulatory factor 2-binding protein-likeHomo sapiens (human)

Compounds (1)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.