| Protein | Synonyms | Taxonomy |
|---|
| Vimentin | | Homo sapiens (human) |
| Potassium channel subfamily K member 10 | Outward rectifying potassium channel protein TREK-2; TREK-2 K(+) channel subunit | Homo sapiens (human) |
| Potassium channel subfamily K member 17 | 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel 2; TALK-2 | Homo sapiens (human) |
| Potassium channel subfamily K member 4 | TWIK-related arachidonic acid-stimulated potassium channel protein; TRAAK; Two pore potassium channel KT4.1; Two pore K(+) channel KT4.1 | Homo sapiens (human) |
| Neprilysin | EC 3.4.24.11; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE | Homo sapiens (human) |
| Potassium voltage-gated channel subfamily H member 2 | Eag homolog; Ether-a-go-go-related gene potassium channel 1; ERG-1; Eag-related protein 1; Ether-a-go-go-related protein 1; H-ERG; hERG-1; hERG1; Voltage-gated potassium channel subunit Kv11.1 | Homo sapiens (human) |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; Voltage-gated calcium channel subunit alpha Cav1.2 | Homo sapiens (human) |
| Myosin light chain kinase, smooth muscle | MLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; Telokin | Homo sapiens (human) |
| Atrial natriuretic peptide receptor 2 | EC 4.6.1.2; Atrial natriuretic peptide receptor type B; ANP-B; ANPR-B; NPR-B; Guanylate cyclase B; GC-B | Homo sapiens (human) |
| Atrial natriuretic peptide receptor 1 | EC 4.6.1.2; Atrial natriuretic peptide receptor type A; ANP-A; ANPR-A; NPR-A; Guanylate cyclase A; GC-A | Homo sapiens (human) |
| Paxillin | | Homo sapiens (human) |
| Natriuretic peptides A | Atrial natriuretic factor prohormone; proANF; Atrial natriuretic peptide prohormone; preproANP; proANP; Atriopeptigen; Cardiodilatin; CDD; preproCDD-ANF | Homo sapiens (human) |
| cGMP-specific 3',5'-cyclic phosphodiesterase | EC 3.1.4.35; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE | Homo sapiens (human) |
| cAMP-dependent protein kinase catalytic subunit alpha | PKA C-alpha; EC 2.7.11.11 | Homo sapiens (human) |
| Integrin beta-5 | | Homo sapiens (human) |
| Potassium voltage-gated channel subfamily A member 5 | HPCN1; Voltage-gated potassium channel HK2; Voltage-gated potassium channel subunit Kv1.5 | Homo sapiens (human) |
| Nitric oxide synthase, brain | EC 1.14.13.39; Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1; bNOS | Homo sapiens (human) |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | PPIase FKBP1B; EC 5.2.1.8; 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; FKBP-12.6; FK506-binding protein 1B; FKBP-1B; Immunophilin FKBP12.6; Rotamase; h-FKBP-12 | Homo sapiens (human) |
| Histone acetyltransferase KAT2B | EC 2.3.1.48; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF; Spermidine acetyltransferase KAT2B; 2.3.1.57 | Homo sapiens (human) |
| Short transient receptor potential channel 1 | TrpC1; Transient receptor protein 1; TRP-1 | Homo sapiens (human) |
| Stromal interaction molecule 1 | | Homo sapiens (human) |
| S-adenosylhomocysteine hydrolase-like protein 1 | DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; Putative adenosylhomocysteinase 2; S-adenosyl-L-homocysteine hydrolase 2; AdoHcyase 2 | Homo sapiens (human) |
| Potassium channel subfamily K member 13 | Tandem pore domain halothane-inhibited potassium channel 1; THIK-1 | Homo sapiens (human) |
| ATP-binding cassette sub-family C member 9 | Sulfonylurea receptor 2 | Homo sapiens (human) |
| Aldehyde dehydrogenase, mitochondrial | EC 1.2.1.3; ALDH class 2; ALDH-E2; ALDHI | Homo sapiens (human) |
| Annexin A2 | Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36 | Homo sapiens (human) |
| Liver carboxylesterase 1 | Acyl-coenzyme A:cholesterol acyltransferase; ACAT; Brain carboxylesterase hBr1; Carboxylesterase 1; CE-1; hCE-1; 3.1.1.1; Cholesteryl ester hydrolase; CEH; 3.1.1.13; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1; 3.1.1.5 | Homo sapiens (human) |
| Transcription factor GATA-4 | GATA-binding factor 4 | Homo sapiens (human) |
| Integrin alpha-1 | CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1 | Homo sapiens (human) |
| Plasma membrane calcium-transporting ATPase 4 | PMCA4; EC 7.2.2.10; Matrix-remodeling-associated protein 1; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4 | Homo sapiens (human) |
| Potassium channel subfamily K member 9 | Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2 | Homo sapiens (human) |
| Voltage-dependent calcium channel subunit alpha-2/delta-2 | Voltage-gated calcium channel subunit alpha-2/delta-2 | Homo sapiens (human) |
| Potassium channel subfamily K member 5 | Acid-sensitive potassium channel protein TASK-2; TWIK-related acid-sensitive K(+) channel 2 | Homo sapiens (human) |
| Aspartyl/asparaginyl beta-hydroxylase | EC 1.14.11.16; Aspartate beta-hydroxylase; ASP beta-hydroxylase; Peptide-aspartate beta-dioxygenase | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| Potassium voltage-gated channel subfamily KQT member 1 | IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1 | Homo sapiens (human) |
| Myotonin-protein kinase | MT-PK; EC 2.7.11.1; DM-kinase; DMK; DM1 protein kinase; DMPK; Myotonic dystrophy protein kinase | Homo sapiens (human) |
| ATP-sensitive inward rectifier potassium channel 11 | IKATP; Inward rectifier K(+) channel Kir6.2; Potassium channel, inwardly rectifying subfamily J member 11 | Homo sapiens (human) |
| Potassium channel subfamily K member 2 | Outward rectifying potassium channel protein TREK-1; TREK-1 K(+) channel subunit; Two pore domain potassium channel TREK-1; Two pore potassium channel TPKC1 | Homo sapiens (human) |
| Annexin A1 | Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35 | Homo sapiens (human) |
| Atrial natriuretic peptide-converting enzyme | EC 3.4.21.-; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10 | Homo sapiens (human) |
| Triadin | | Homo sapiens (human) |
| Potassium channel subfamily K member 3 | Acid-sensitive potassium channel protein TASK-1; TWIK-related acid-sensitive K(+) channel 1; Two pore potassium channel KT3.1; Two pore K(+) channel KT3.1 | Homo sapiens (human) |
| Potassium channel subfamily K member 18 | TWIK-related individual potassium channel; TWIK-related spinal cord potassium channel | Homo sapiens (human) |
| Leiomodin-1 | 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; Leiomodin, muscle form; Smooth muscle leiomodin; SM-Lmod; Thyroid-associated ophthalmopathy autoantigen | Homo sapiens (human) |
| Chloride intracellular channel protein 2 | XAP121 | Homo sapiens (human) |
| Sorbin and SH3 domain-containing protein 1 | Ponsin; SH3 domain protein 5; SH3P12; c-Cbl-associated protein; CAP | Homo sapiens (human) |
| T-box transcription factor TBX5 | T-box protein 5 | Homo sapiens (human) |
| Vinculin | Metavinculin; MV | Homo sapiens (human) |
| Dysferlin | Dystrophy-associated fer-1-like protein; Fer-1-like protein 1 | Homo sapiens (human) |
| Nebulin | | Homo sapiens (human) |
| C-type natriuretic peptide | | Homo sapiens (human) |
| Dystrophin | | Homo sapiens (human) |
| Desmin | | Homo sapiens (human) |
| Cardiac phospholamban | PLB | Homo sapiens (human) |
| Caldesmon | CDM | Homo sapiens (human) |
| Titin | EC 2.7.11.1; Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14 | Homo sapiens (human) |
| Sarcolipin | | Homo sapiens (human) |
| Homeobox protein Nkx-2.5 | Cardiac-specific homeobox; Homeobox protein CSX; Homeobox protein NK-2 homolog E | Homo sapiens (human) |
| Annexin A6 | 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70 | Homo sapiens (human) |
| Potassium channel subfamily K member 15 | Acid-sensitive potassium channel protein TASK-5; TWIK-related acid-sensitive K(+) channel 5; Two pore potassium channel KT3.3; Two pore K(+) channel KT3.3 | Homo sapiens (human) |
| Caveolin-3 | M-caveolin | Homo sapiens (human) |
| Potassium channel subfamily K member 1 | Inward rectifying potassium channel protein TWIK-1; Potassium channel K2P1; Potassium channel KCNO1 | Homo sapiens (human) |
| Telethonin | Titin cap protein | Homo sapiens (human) |
| Vinexin | SH3-containing adapter molecule 1; SCAM-1; Sorbin and SH3 domain-containing protein 3 | Homo sapiens (human) |
| Troponin I, cardiac muscle | Cardiac troponin I | Homo sapiens (human) |
| Sorcin | 22 kDa protein; CP-22; CP22; V19 | Homo sapiens (human) |
| Myosin-11 | Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHC | Homo sapiens (human) |
| Tripartite motif-containing protein 72 | Mitsugumin-53; Mg53 | Homo sapiens (human) |
| Potassium channel subfamily K member 16 | 2P domain potassium channel Talk-1; TWIK-related alkaline pH-activated K(+) channel 1; TALK-1 | Homo sapiens (human) |
| A-kinase anchor protein 9 | AKAP-9; A-kinase anchor protein 350 kDa; AKAP 350; hgAKAP 350; A-kinase anchor protein 450 kDa; AKAP 450; AKAP 120-like protein; Centrosome- and Golgi-localized PKN-associated protein; CG-NAP; Protein hyperion; Protein kinase A-anchoring protein 9; PRKA9; | Homo sapiens (human) |
| WW domain-containing transcription regulator protein 1 | Transcriptional coactivator with PDZ-binding motif | Homo sapiens (human) |
| Potassium channel subfamily K member 12 | Tandem pore domain halothane-inhibited potassium channel 2; THIK-2 | Homo sapiens (human) |
| Ran guanine nucleotide release factor | RanGNRF; Ran-binding protein MOG1 | Homo sapiens (human) |
| Potassium channel subfamily K member 6 | Inward rectifying potassium channel protein TWIK-2; TWIK-originated similarity sequence | Homo sapiens (human) |
| Potassium channel subfamily K member 7 | | Homo sapiens (human) |
| Talin-1 | | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| carbon monoxide | Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed) |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| nitroglycerin | A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives. |
| Ethanol | A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Sodium | A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| cyclic gmp | Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed) |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| glyceryl 1,2-dinitrate | |
| bay 58-2667 | activates guanylyl cyclase; structure in first source |