Pathways > Muscle contraction
Page last updated: 2024-10-06

Muscle contraction

Proteins (77)

ProteinSynonymsTaxonomy
VimentinHomo sapiens (human)
Potassium channel subfamily K member 10Outward rectifying potassium channel protein TREK-2; TREK-2 K(+) channel subunitHomo sapiens (human)
Potassium channel subfamily K member 172P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel 2; TALK-2Homo sapiens (human)
Potassium channel subfamily K member 4TWIK-related arachidonic acid-stimulated potassium channel protein; TRAAK; Two pore potassium channel KT4.1; Two pore K(+) channel KT4.1Homo sapiens (human)
NeprilysinEC 3.4.24.11; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFEHomo sapiens (human)
Potassium voltage-gated channel subfamily H member 2Eag homolog; Ether-a-go-go-related gene potassium channel 1; ERG-1; Eag-related protein 1; Ether-a-go-go-related protein 1; H-ERG; hERG-1; hERG1; Voltage-gated potassium channel subunit Kv11.1Homo sapiens (human)
Voltage-dependent L-type calcium channel subunit alpha-1CCalcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; Voltage-gated calcium channel subunit alpha Cav1.2Homo sapiens (human)
Myosin light chain kinase, smooth muscleMLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; TelokinHomo sapiens (human)
Atrial natriuretic peptide receptor 2EC 4.6.1.2; Atrial natriuretic peptide receptor type B; ANP-B; ANPR-B; NPR-B; Guanylate cyclase B; GC-BHomo sapiens (human)
Atrial natriuretic peptide receptor 1EC 4.6.1.2; Atrial natriuretic peptide receptor type A; ANP-A; ANPR-A; NPR-A; Guanylate cyclase A; GC-AHomo sapiens (human)
PaxillinHomo sapiens (human)
Natriuretic peptides AAtrial natriuretic factor prohormone; proANF; Atrial natriuretic peptide prohormone; preproANP; proANP; Atriopeptigen; Cardiodilatin; CDD; preproCDD-ANFHomo sapiens (human)
cGMP-specific 3',5'-cyclic phosphodiesteraseEC 3.1.4.35; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDEHomo sapiens (human)
cAMP-dependent protein kinase catalytic subunit alphaPKA C-alpha; EC 2.7.11.11Homo sapiens (human)
Integrin beta-5Homo sapiens (human)
Potassium voltage-gated channel subfamily A member 5HPCN1; Voltage-gated potassium channel HK2; Voltage-gated potassium channel subunit Kv1.5Homo sapiens (human)
Nitric oxide synthase, brainEC 1.14.13.39; Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1; bNOSHomo sapiens (human)
Peptidyl-prolyl cis-trans isomerase FKBP1BPPIase FKBP1B; EC 5.2.1.8; 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; FKBP-12.6; FK506-binding protein 1B; FKBP-1B; Immunophilin FKBP12.6; Rotamase; h-FKBP-12Homo sapiens (human)
Histone acetyltransferase KAT2BEC 2.3.1.48; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF; Spermidine acetyltransferase KAT2B; 2.3.1.57Homo sapiens (human)
Short transient receptor potential channel 1TrpC1; Transient receptor protein 1; TRP-1Homo sapiens (human)
Stromal interaction molecule 1Homo sapiens (human)
S-adenosylhomocysteine hydrolase-like protein 1DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; Putative adenosylhomocysteinase 2; S-adenosyl-L-homocysteine hydrolase 2; AdoHcyase 2Homo sapiens (human)
Potassium channel subfamily K member 13Tandem pore domain halothane-inhibited potassium channel 1; THIK-1Homo sapiens (human)
ATP-binding cassette sub-family C member 9Sulfonylurea receptor 2Homo sapiens (human)
Aldehyde dehydrogenase, mitochondrialEC 1.2.1.3; ALDH class 2; ALDH-E2; ALDHIHomo sapiens (human)
Annexin A2Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36Homo sapiens (human)
Liver carboxylesterase 1Acyl-coenzyme A:cholesterol acyltransferase; ACAT; Brain carboxylesterase hBr1; Carboxylesterase 1; CE-1; hCE-1; 3.1.1.1; Cholesteryl ester hydrolase; CEH; 3.1.1.13; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1; 3.1.1.5Homo sapiens (human)
Transcription factor GATA-4GATA-binding factor 4Homo sapiens (human)
Integrin alpha-1CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1Homo sapiens (human)
Plasma membrane calcium-transporting ATPase 4PMCA4; EC 7.2.2.10; Matrix-remodeling-associated protein 1; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4Homo sapiens (human)
Potassium channel subfamily K member 9Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2Homo sapiens (human)
Voltage-dependent calcium channel subunit alpha-2/delta-2Voltage-gated calcium channel subunit alpha-2/delta-2Homo sapiens (human)
Potassium channel subfamily K member 5Acid-sensitive potassium channel protein TASK-2; TWIK-related acid-sensitive K(+) channel 2Homo sapiens (human)
Aspartyl/asparaginyl beta-hydroxylaseEC 1.14.11.16; Aspartate beta-hydroxylase; ASP beta-hydroxylase; Peptide-aspartate beta-dioxygenaseHomo sapiens (human)
Calmodulin-1Homo sapiens (human)
Potassium voltage-gated channel subfamily KQT member 1IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1Homo sapiens (human)
Myotonin-protein kinaseMT-PK; EC 2.7.11.1; DM-kinase; DMK; DM1 protein kinase; DMPK; Myotonic dystrophy protein kinaseHomo sapiens (human)
ATP-sensitive inward rectifier potassium channel 11IKATP; Inward rectifier K(+) channel Kir6.2; Potassium channel, inwardly rectifying subfamily J member 11Homo sapiens (human)
Potassium channel subfamily K member 2Outward rectifying potassium channel protein TREK-1; TREK-1 K(+) channel subunit; Two pore domain potassium channel TREK-1; Two pore potassium channel TPKC1Homo sapiens (human)
Annexin A1Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35Homo sapiens (human)
Atrial natriuretic peptide-converting enzymeEC 3.4.21.-; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10Homo sapiens (human)
TriadinHomo sapiens (human)
Potassium channel subfamily K member 3Acid-sensitive potassium channel protein TASK-1; TWIK-related acid-sensitive K(+) channel 1; Two pore potassium channel KT3.1; Two pore K(+) channel KT3.1Homo sapiens (human)
Potassium channel subfamily K member 18TWIK-related individual potassium channel; TWIK-related spinal cord potassium channelHomo sapiens (human)
Leiomodin-164 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; Leiomodin, muscle form; Smooth muscle leiomodin; SM-Lmod; Thyroid-associated ophthalmopathy autoantigenHomo sapiens (human)
Chloride intracellular channel protein 2XAP121Homo sapiens (human)
Sorbin and SH3 domain-containing protein 1Ponsin; SH3 domain protein 5; SH3P12; c-Cbl-associated protein; CAPHomo sapiens (human)
T-box transcription factor TBX5T-box protein 5Homo sapiens (human)
VinculinMetavinculin; MVHomo sapiens (human)
DysferlinDystrophy-associated fer-1-like protein; Fer-1-like protein 1Homo sapiens (human)
NebulinHomo sapiens (human)
C-type natriuretic peptideHomo sapiens (human)
DystrophinHomo sapiens (human)
DesminHomo sapiens (human)
Cardiac phospholambanPLBHomo sapiens (human)
CaldesmonCDMHomo sapiens (human)
TitinEC 2.7.11.1; Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14Homo sapiens (human)
SarcolipinHomo sapiens (human)
Homeobox protein Nkx-2.5Cardiac-specific homeobox; Homeobox protein CSX; Homeobox protein NK-2 homolog EHomo sapiens (human)
Annexin A667 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70Homo sapiens (human)
Potassium channel subfamily K member 15Acid-sensitive potassium channel protein TASK-5; TWIK-related acid-sensitive K(+) channel 5; Two pore potassium channel KT3.3; Two pore K(+) channel KT3.3Homo sapiens (human)
Caveolin-3M-caveolinHomo sapiens (human)
Potassium channel subfamily K member 1Inward rectifying potassium channel protein TWIK-1; Potassium channel K2P1; Potassium channel KCNO1Homo sapiens (human)
TelethoninTitin cap proteinHomo sapiens (human)
VinexinSH3-containing adapter molecule 1; SCAM-1; Sorbin and SH3 domain-containing protein 3Homo sapiens (human)
Troponin I, cardiac muscleCardiac troponin IHomo sapiens (human)
Sorcin22 kDa protein; CP-22; CP22; V19Homo sapiens (human)
Myosin-11Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHCHomo sapiens (human)
Tripartite motif-containing protein 72Mitsugumin-53; Mg53Homo sapiens (human)
Potassium channel subfamily K member 162P domain potassium channel Talk-1; TWIK-related alkaline pH-activated K(+) channel 1; TALK-1Homo sapiens (human)
A-kinase anchor protein 9AKAP-9; A-kinase anchor protein 350 kDa; AKAP 350; hgAKAP 350; A-kinase anchor protein 450 kDa; AKAP 450; AKAP 120-like protein; Centrosome- and Golgi-localized PKN-associated protein; CG-NAP; Protein hyperion; Protein kinase A-anchoring protein 9; PRKA9;Homo sapiens (human)
WW domain-containing transcription regulator protein 1Transcriptional coactivator with PDZ-binding motifHomo sapiens (human)
Potassium channel subfamily K member 12Tandem pore domain halothane-inhibited potassium channel 2; THIK-2Homo sapiens (human)
Ran guanine nucleotide release factorRanGNRF; Ran-binding protein MOG1Homo sapiens (human)
Potassium channel subfamily K member 6Inward rectifying potassium channel protein TWIK-2; TWIK-originated similarity sequenceHomo sapiens (human)
Potassium channel subfamily K member 7Homo sapiens (human)
Talin-1Homo sapiens (human)

Compounds (19)

CompoundDescription
hydronium ion
Nitric OxideA free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
carbon monoxideCarbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
nitroglycerinA volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
EthanolA clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
cyclic gmpGuanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glyceryl 1,2-dinitrate
bay 58-2667activates guanylyl cyclase; structure in first source
chemdatabank.com