Page last updated: 2024-09-27
Vasa Praevia
Pregnancy complication where fetal blood vessels, normally inside the umbilical cord, are left unprotected and cross FETAL MEMBRANES. It is associated with antepartum bleeding and FETAL DEATH and STILLBIRTH due to exsanguination.
Synonyms(2)
| Synonym |
|---|
| Vasa Praevia |
| Vasa Previa |
Research Excerpts
Overview
Research
Studies (4)
| Timeframe | Studies, This Condition (%) | All Conditions % |
|---|
| pre-1990 | 0 (0.00) | 23.3326 |
| 1990's | 0 (0.00) | 12.5806 |
| 2000's | 0 (0.00) | 18.1394 |
| 2010's | 3 (75.00) | 28.8240 |
| 2020's | 1 (25.00) | 9.53 |
Protein Targets (53)
| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| pregnane X receptor | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| AR protein | 3 | 0 | 0 | 3 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| galanin receptor type 3 | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Glucocorticoid receptor | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| ORF73 | 0 | 0 | 1 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Sex hormone-binding globulin | 0 | 0 | 1 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Alpha-synuclein | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A1 | 0 | 1 | 0 | 1 |
| Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| UDP-glucuronosyltransferase 1A10 | 0 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |