segetalin A: isolated from Vaccaria segetalis; structure in first source [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 10483858 |
| CHEMBL ID | 378333 |
| SCHEMBL ID | 151176 |
| MeSH ID | M0267179 |
| Synonym |
|---|
| segetalin a |
| CHEMBL378333 |
| segetalin a trifluoroacetic acid salt |
| 161875-97-4 |
| SCHEMBL151176 |
| segetalin-a |
| DTXSID10440594 |
| (3s,9s,12s,15s,18s)-12-(1h-indol-3-ylmethyl)-9-methyl-3,15-di(propan-2-yl)-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosane-2,5,8,11,14,17-hexone |
| MS-30690 |
| HY-107246 |
| CS-0027754 |
| AKOS040760706 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID402827 | Estrogen-like activity in ovariectomized SD rat assessed as increase in uterus weight at 2.5 mg/kg, sc administered daily for 14 days | 1997 | Journal of natural products, Mar, Volume: 60, Issue:3 ISSN: 0163-3864 | Cyclic peptides from higher plants. 34. Segetalins G and H, structures and estrogen-like activity of cyclic pentapeptides from Vaccaria segetalis. |
| AID270571 | Vasorelaxation effect against norepinephrine-induced contraction of rat thoracic aortic ring with endothelium at 100 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17 ISSN: 0960-894X | Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis. |
| AID270573 | Vasorelaxation effect against norepinephrine-induced contraction of rat thoracic aortic ring without endothelium at 100 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 16, Issue:17 ISSN: 0960-894X | Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis. |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| segetalin b | 1997 | 2006 | 22.5 | high | 0 | 0 | 1 | 1 | 0 | 0 |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| methanol | alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound | amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite | 2011 | 2011 | 13.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| pyrroles | pyrrole; secondary amine | 2007 | 2007 | 17.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | ||
| ethyl acetate | acetate ester; ethyl ester; volatile organic compound | EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor; metabolite; polar aprotic solvent; Saccharomyces cerevisiae metabolite | 2011 | 2011 | 13.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| phenyl acetate | benzenes; phenyl acetates | 2011 | 2011 | 13.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | ||
| oxytocin | heterodetic cyclic peptide; peptide hormone | oxytocic; vasodilator agent | 1995 | 1995 | 29.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 | |
| segetalin b | 1995 | 2011 | 23.0 | high | 0 | 0 | 2 | 0 | 1 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|