Page last updated: 2024-12-08

salivaricin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

salivaricin A: from Streptococcus salivarius; MW 2315 kDa; 22-residue peptide containing one lanthionine & two beta-methyllanthionine residues; amino acid sequence given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID172832
SCHEMBL ID526308
MeSH IDM0220210

Synonyms (14)

Synonym
einecs 275-615-2
salivaricin a
cyclotetrasiloxane, 2,4,6,8-tetramethyl-2,4,6,8-tetrakis(3-acryloxypropyl)-
71550-64-6
2,4,6,8-tetramethyl-2,4,6,8-tetrakis(3-acryloyloxypropyl) cyclotetrasiloxane
(2,4,6,8-tetramethylcyclotetrasiloxane-2,4,6,8-tetrayl)tetrakis(propane-1,3-diyl) tetraacrylate
2-propenoic acid, 1,1',1'',1'''-((2,4,6,8-tetramethylcyclotetrasiloxane-2,4,6,8-tetrayl)tetra-3,1-propanediyl) ester
2-propenoic acid, (2,4,6,8-tetramethylcyclotetrasiloxane-2,4,6,8-tetrayl)tetra-3,1-propanediyl ester
SCHEMBL526308
3-{2,4,6,8-tetramethyl-4,6,8-tris[3-(prop-2-enoyloxy)propyl]-1,3,5,7,2,4,6,8-tetraoxatetrasilocan-2-yl}propyl prop-2-enoate
(2,4,6,8-tetramethyl-1,3,5,7,2,4,6,8-tetroxatetrasilocane-2,4,6,8-tetrayl)tetra(propane-3,1-diyl) tetraprop-2-enoate
DTXSID70992100
(2,4,6,8-tetramethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane-2,4,6,8-tetrayl)tetrakis(propane-3,1-diyl) tetraacrylate
(2,4,6,8-tetramethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane-2,4,6,8-tetrayl)tetrakis(propane-3,1-diyl)tetraacrylate

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
"To determine whether dosing with bacteriocin-producing Streptococcus salivarius following an antimicrobial mouthwash effects a change in oral malodour parameters and in the composition of the oral microbiota of subjects with halitosis."( A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters.
Burton, JP; Chilcott, CN; Moore, CJ; Speiser, G; Tagg, JR, 2006
)
0.33
"The colonization efficacies of salivaricin A (SalA)-producing Streptococcus salivarius strains 20P3 and 5 were compared when given in milk to 219 children, using either 2-day or 9-day dosing regimens."( The effect of ingestion of milk supplemented with salivaricin A-producing Streptococcus salivarius on the bacteriocin-like inhibitory activity of streptococcal populations on the tongue.
Dierksen, KP; Inglis, M; Moore, CJ; Tagg, JR; Wescombe, PA, 2007
)
0.88
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (21)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (14.29)18.2507
2000's10 (47.62)29.6817
2010's6 (28.57)24.3611
2020's2 (9.52)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.67 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.76%)5.53%
Reviews2 (9.52%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other18 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]