Compounds > propyl nitrate
Page last updated: 2024-12-05

propyl nitrate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

propyl nitrate: C3-H7-N-O3 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID12307
CHEMBL ID188554
SCHEMBL ID324772
MeSH IDM0379974

Synonyms (33)

Synonym
propylester kyseliny dusicne
983r6rcp6f ,
nitrate de propyle normal
n-propyl nitrate [un1865] [flammable liquid]
unii-983r6rcp6f
propylester kyseliny dusicne [czech]
hsdb 7198
monopropyl nitrate
nitrate de propyle normal [french]
einecs 210-985-0
un1865
brn 1701406
nitric acid, propyl ester
propyl nitrate
inchi=1/c3h7no3/c1-2-3-7-4(5)6/h2-3h2,1h
n-propyl nitrate
bdbm50156306
1-nitrooxy-propane
CHEMBL188554 ,
AKOS006274317
627-13-4
nitric acid propyl ester
FT-0632646
propyl nitrate [mi]
un-1865
SCHEMBL324772
DTXSID2060834
n-c3h7ono2
un 1865
propylnitrat
Q18816316
BS-29076
n-propyl nitrate (stabilized)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID248828Tested for inhibition of ferrous salt/ascorbate induced lipidic peroxidation of membrane lipid of rat hepatocytes at 1 mM; IA = inactive2004Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
AID264515Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips2006Journal of medicinal chemistry, May-18, Volume: 49, Issue:10
NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties.
AID246502Vasodilating activity in rat aorta strip in absence of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ)2004Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
AID264514Antioxidant activity assessed as inhibition of TBARS production in ferrous salt/ascorbate-induced lipid peroxidation in Wistar rat liver microsomal membrane at 1 mM2006Journal of medicinal chemistry, May-18, Volume: 49, Issue:10
NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties.
AID264517Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips at 100 uM in presence of 1 uM ODQ2006Journal of medicinal chemistry, May-18, Volume: 49, Issue:10
NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties.
AID246571Vasodilating activity in rat aorta strip in presence of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) at 100 uM2004Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 45.81

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index45.81 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.55 (4.65)
Search Engine Demand Index63.74 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (45.81)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nitrates
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.		2.6730monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
4-cresol
4-cresol: RN given refers to parent cpd. p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.		2.4320cresolEscherichia coli metabolite;
human metabolite;
uremic toxin
peracetic acid
Peracetic Acid: A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.. peracetic acid : A peroxy acid that is acetic acid in which the OH group is substituted by a hydroperoxy group. It is a versatile oxidising agent that is used as a disinfectant.		210a peroxy aciddisinfectant;
oxidising agent
methyl nitrate
methyl nitrate: C-H3-N-O3		2.4520
peroxyacetyl nitrate
peroxyacetyl nitrate: important air pollutant; structure		210
peroxypropionyl nitrate
[no description available]		210
propylene glycol dinitrate
propylene glycol dinitrate: major volatile constituent of Otto Fuel II liquid propellant that causes vasodilation, lowered blood pressure, methemoglobin formation; monoamine oxidase inhibitor		2.0310
ozone
Ozone: The unstable triatomic form of oxygen, O3. It is a powerful oxidant that is produced for various chemical and industrial uses. Its production is also catalyzed in the ATMOSPHERE by ULTRAVIOLET RAY irradiation of oxygen or other ozone precursors such as VOLATILE ORGANIC COMPOUNDS and NITROGEN OXIDES. About 90% of the ozone in the atmosphere exists in the stratosphere (STRATOSPHERIC OZONE).. ozone : An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.		2.1710elemental molecule;
gas molecular entity;
reactive oxygen species;
triatomic oxygen		antiseptic drug;
disinfectant;
electrophilic reagent;
greenhouse gas;
mutagen;
oxidising agent;
tracer
butylated hydroxytoluene
2,6-di-tert-butyl-4-methylphenol : A member of the class of phenols that is 4-methylphenol substituted by tert-butyl groups at positions 2 and 6.		2.4320phenolsantioxidant;
ferroptosis inhibitor;
food additive;
geroprotector
2,2,5,7,8-pentamethyl-1-hydroxychroman
2,2,5,7,8-pentamethyl-1-hydroxychroman: a Vitamin E derivative. chromanol : Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.		2.4320
4-ethoxy-3-phenylsulfonylfuroxan
[no description available]		2.4320
ConditionIndicatedRelationship StrengthStudiesTrials
Arteriosclerosis
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.		02.0210
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		02.0310