Compounds > n-acetyltryptophan methyl ester
Page last updated: 2024-12-07

n-acetyltryptophan methyl ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-acetyltryptophan methyl ester: RN given refers to (L)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID102337
CHEMBL ID1276128
SCHEMBL ID468840
MeSH IDM0094359

Synonyms (35)

Synonym
l-tryptophan, n-acetyl-, methyl ester (9ci)
2824-57-9
methyl acetyltryptophanate
methyl n-acetyl-l-tryptophanate
tryptophan, n-acetyl-, methyl ester, l- (6ci,7ci,8ci)
l-tryptophan, n-acetyl-, methyl ester
acetyltryptophan methyl ester
methyl l-n-acetyltryptophanate
methyl (2s)-2-acetamido-3-(1h-indol-3-yl)propanoate
CHEMBL1276128
unii-mup4y18zq5
n-acetyltryptophan methyl ester
mup4y18zq5 ,
ac-trp-ome
tryptophan, n-acetyl-, methyl ester, l-
n-acetyl-l-tryptophan methyl ester
n.alpha.-acetyl-l-tryptophan methyl ester
mfcd00022759
n-alpha-actetyl-l-tryptophane methyl ester (ac-l-trp-ome)
SCHEMBL468840
XZECNVJPYDPBAM-ZDUSSCGKSA-N
methyl 2-(acetylamino)-3-(1h-indol-3-yl)propanoate #
AS-63456
J-017014
ac-l-trp-ome
36060-94-3
CS-0112520
methyl acetyl-l-tryptophanate
(s)-methyl 2-acetamido-3-(1h-indol-3-yl)propanoate
Q27284236
D97613
DTXSID70950962
n-[3-(1h-indol-3-yl)-1-methoxy-1-oxopropan-2-yl]ethanimidic acid
AKOS016843133
l-tryptophan,n-acetyl-,methyl ester
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (8)

Assay IDTitleYearJournalArticle
AID537678Antioxidant activity assessed as inhibition of nitric oxide-induced oxidation of non-fluorescent DAF-2 by fluorescence assay2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537673Antioxidant activity assessed as superoxide radical scavenging activity by NBT reduction assay2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537676Antioxidant activity assessed as inhibition of HOCl-induced oxidation of DHR by rhodamine 123 staining2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537680Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in presence of NaHCO32010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537677Antioxidant activity assessed as inhibition of singlet oxygen-induced oxidation of DHR by rhodamine 123 staining2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537679Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in absence of NaHCO32010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537674Antioxidant activity assessed as inhibition of H2O2-induced oxidation of lucigenin2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
AID537675Antioxidant activity assessed as trolox equivalent of peroxyl radical scavenging activity by ORAC assay2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Antioxidant activity of unexplored indole derivatives: synthesis and screening.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.34

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.34 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.34)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
tryptamine
[no description available]		2.0510aminoalkylindole;
aralkylamino compound;
indole alkaloid;
tryptamines		human metabolite;
mouse metabolite;
plant metabolite
uracil
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder		1.9710pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
diethyl pyrocarbonate
Diethyl Pyrocarbonate: Preservative for wines, soft drinks, and fruit juices and a gentle esterifying agent.. diethyl pyrocarbonate : The diethyl ester of dicarbonic acid.		1.9610acyclic carboxylic anhydride
histidine
Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.		1.9610amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
tryptophan
Tryptophan: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.. tryptophan : An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.		3.0750erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
skatole
[no description available]		1.9710methylindolehuman metabolite;
mammalian metabolite
methyl tryptophan, (l-trp)-isomer
[no description available]		2.0510
5-bromo-1,3-dimethyluracil
5-bromo-1,3-dimethyluracil: structure given in first source		1.9710
alpha-chymotrypsin
Chymotrypsin: A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.		2.3620
ConditionIndicatedRelationship StrengthStudiesTrials