Compounds > methanesulfonyl chloride
Page last updated: 2024-11-05

methanesulfonyl chloride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Methanesulfonyl chloride (MsCl) is a colorless liquid with a pungent odor. It is a versatile reagent in organic chemistry and is used as a sulfonylating agent. MsCl is prepared by reacting methane with sulfuryl chloride (SO2Cl2) in the presence of a catalyst such as iron. Methanesulfonyl chloride is a powerful electrophile and is used to introduce a methanesulfonyl group (Ms) onto various organic molecules, such as alcohols, amines, and thiols. This sulfonylation reaction is often used to protect these functional groups or to activate them for subsequent reactions. Methanesulfonyl chloride is also used in the synthesis of pharmaceuticals and other fine chemicals. Due to its reactivity and versatility, methanesulfonyl chloride has been extensively studied and is a valuable reagent for organic chemists. '

Cross-References

ID SourceID
PubMed CID31297
SCHEMBL ID1562
MeSH IDM0095754

Synonyms (110)

Synonym
methansulfonylchlorid
nsc 15039
ai3-52234
hsdb 5605
un3246
einecs 204-706-1
chloromethyl sulfone
nsc15039
mesyl chloride
methanesulfonic acid chloride
124-63-0
methanesulfuryl chloride
methyl sulfochloride
chloro methyl sulfone
methylsulfonyl chloride
nsc-15039
methyl sulfonyl chloride
methanesulfonyl chloride ,
methanesulphonyl chloride
inchi=1/ch3clo2s/c1-5(2,3)4/h1h
methanesulfonyl chloride, >=99.7%
AKOS000269070
NCGC00248776-01
cas-124-63-0
dtxcid601615
dtxsid1021615 ,
tox21_200643
NCGC00258197-01
M0094
methane sulphonyl chloride
methanesulfonyl chloride [un3246] [poison]
b17ewy1r7q ,
unii-b17ewy1r7q
ec 204-706-1
mesylchloride
STL264180
methanesulfonyl chloride [hsdb]
methanesulfonyl chloride [mi]
SCHEMBL1562
metanesulfonyl chloride
methane- sulfonyl chloride
mesylchoride
methane-sulfonyl-chloride
methyl sulphonyl chloride
methariesulfonyl chloride
methane sulfonyl chloride ,
methanesulonyl chloride
methanesulfonic chloride
methansulfonylchloride
methanesulfonylchlorid
me thane sulfonyl chloride
methysulfonyl chloride
methanesulphonylchloride
methylsulphonyl chloride
methane sulphonic acid chloride
methanesulfonyl cloride
methanesulfonoyl chloride
methansulphonylchloride
methane sulphonyl choride
mscl
methanesulphonyl choride
mesyl chlorid
meso2-cl
methansulphonyl chloride
methylsulfonyl choride
methanesulphonyl cloride
methane-sulfonyl chloride
methanesulphonic acid chloride
methansulfonyl-chloride
methanesulfonic acid chlorid
clso2me
methanesulforiylchloride
methanesuiphonyl chloride
methanesulphonyl-chloride
methane-sulfonylchloride
methane-sulphonyl chloride
methylsufonyl chloride
methylsulfonic chloride
methanesulfonyl choride
ms-cl
methanesulphonic chloride
methanesulfonyl chlorine
methylsulfonylchloride
methane sulfonylchloride
methanesulfonyl chlorid
methane sulfonic acid chloride
ch3so2cl
methanesufonyl chloride
methyl-sulfonyl chloride
methanesulfonoic acid chloride
methanesulfonyl-chloride
methanesul-fonyl chloride
methane sulphonylchloride
ch3s(o)2cl
methanesulfonly chloride
meso2cl
mesylic acid chloride
methylsulfonyl -chloride
methanesulfonlychloride
methansulfonyl chloride
methanesufonylchloride
Q-201363
STR00131
mfcd00007454
methanesulfonyl chloride, puriss., >=99.0% (at)
methanesulfonyl chloride, purum, >=98.0% (at)
methanesulfonyl chloride, >=99%
methanesulfonyl chloride, 98%
Q417706
methanesulfonylchloride-d3
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 59.22

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index59.22 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.81 (4.65)
Search Engine Demand Index92.46 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (59.22)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
4-aminopyridine
[no description available]		2.0810aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
soman
Soman: An organophosphorus compound that inhibits cholinesterase. It causes seizures and has been used as a chemical warfare agent.		1.9610phosphonic ester
isocarbostyril
isoquinolinone : An isoquinoline containing one or more oxo groups.		2.0310isoquinolines
4-dimethylaminopyridine
4-dimethylaminopyridine: catalyst for acetylation of hydroxy cpds; structure		2.0810dialkylarylamine;
tertiary amino compound
titanium
Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.		2.0310titanium group element atom
chlorine
Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.		1.9910diatomic chlorine;
gas molecular entity		bleaching agent
sodium hydride
[no description available]		2.0410
sodium azide
Sodium Azide: A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed). sodium azide : The sodium salt of hydrogen azide (hydrazoic acid).		2.0810inorganic sodium saltantibacterial agent;
explosive;
mitochondrial respiratory-chain inhibitor;
mutagen
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.		2.08101,2,3-triazole
morphinans
Morphinans: Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They include some of the OPIOIDS found in PAPAVER that are used as ANALGESICS.		2.0410isoquinoline alkaloid fundamental parent;
morphinane alkaloid
oligomycin a
[no description available]		2.0810antibiotic antifungal agent;
diketone;
oligomycin;
pentol		antineoplastic agent;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
nematicide
oligomycins
Oligomycins: A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).		2.0810
ConditionIndicatedRelationship StrengthStudiesTrials
Abnormalities, Autosome
[description not available]		01.9910
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		01.9610