| Assay ID | Title | Year | Journal | Article |
|---|
| AID1398282 | Clearance in C57Bl6 mouse at 10 mg/kg, iv by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398283 | Terminal half life in rat at 1 mg/kg, iv | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398287 | Volume of distribution at steady state in rat at 1 mg/kg, iv | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398268 | Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398267 | Binding affinity to His-tagged Myc (unknown origin) expressed in Escherichia coli BL21 by Bio-FET analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398278 | AUC (0 to infinity) in C57Bl6 mouse at 10 mg/kg, iv by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398286 | MRT in rat at 1 mg/kg, iv | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398285 | AUMC (0 to infinity) in rat at 1 mg/kg, iv | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398276 | Drug metabolism in rat liver microsomes assessed as oxidized furan ion formation by measuring parent compound remaining at 5 uM after 45 mins by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398275 | Drug metabolism in rat liver microsomes assessed as oxidized furan ion formation by measuring parent compound remaining at 5 uM after 25 mins by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398281 | Volume of distribution at steady state in C57Bl6 mouse at 10 mg/kg, iv by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398284 | AUC (0 to infinity) in rat at 1 mg/kg, iv | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398263 | Binding affinity to His-tagged Myc (unknown origin) expressed in Escherichia coli BL21 at 10 uM by Bio-FET analysis relative to KJ-Pyr-9 | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398262 | Solubility in pH 6 MES buffer by dynamic light scattering assay | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398279 | AUMC (0 to infinity) in C57Bl6 mouse at 10 mg/kg, iv by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398271 | Binding affinity to biotin-labeled EBOX dsDNA (unknown origin) at 10 uM measured over 2.5 mins by SPR analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398274 | Drug metabolism in rat liver microsomes assessed as oxidized furan ion formation by measuring parent compound remaining at 5 uM after 15 mins by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398265 | Binding affinity to His-tagged monomeric Max (unknown origin) expressed in Escherichia coli BL21 at 10 uM by Bio-FET analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398270 | Inhibition of biotin-labeled EBOX dsDNA binding to Myc-Max (unknown origin) at 10 uM preincubated for 15 mins followed by test compound-protein mixture addition to biotin-labeled EBOX dsDNA immobilized chip measured over 2.5 mins by SPR analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398272 | Drug metabolism in rat liver microsomes assessed as oxidized furan ion formation by measuring parent compound remaining at 5 uM after 3 mins by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398288 | Clearance in rat at 1 mg/kg, iv | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398264 | Binding affinity to His-tagged Myc/Max (unknown origin) expressed in Escherichia coli BL21 at 10 uM by Bio-FET analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398273 | Drug metabolism in rat liver microsomes assessed as oxidized furan ion formation by measuring parent compound remaining at 5 uM after 7 mins by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398280 | MRT in C57Bl6 mouse at 10 mg/kg, iv by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398277 | Terminal half life in C57Bl6 mouse at 10 mg/kg, iv by LC-MS analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| AID1398266 | Binding affinity to His-tagged dimeric Max (unknown origin) expressed in Escherichia coli BL21 at 10 uM by Bio-FET analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Synthetic molecules for disruption of the MYC protein-protein interface. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |