Page last updated: 2024-11-13
isocyclosporin a
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
isocyclosporin A: structural analog of cyclosporin A [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 101607771 |
| CHEMBL ID | 4560592 |
| MeSH ID | M0191342 |
Synonyms (5)
| Synonym |
|---|
| 59865-16-6 |
| isocyclosporin a |
| isocyclosporina |
| isocyclosporin-a |
| CHEMBL4560592 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1532162 | 1,9-decadiene/aqueous buffer solution partition coefficient, log D of the compound in PBS at pH 7.4 by shake flask method | 2018 | Journal of medicinal chemistry, 12-27, Volume: 61, Issue:24 | Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility. |
| AID1532161 | Thermodynamic aqueous solubility of compound in pH 7.4 PBS by UPLC-MS analysis | 2018 | Journal of medicinal chemistry, 12-27, Volume: 61, Issue:24 | Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility. |
| AID1532163 | Apparent permeability in low-efflux MDCK2 cells at 2 uM by lucifer yellow dye-based UPLC-MS analysis | 2018 | Journal of medicinal chemistry, 12-27, Volume: 61, Issue:24 | Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.53
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.53) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||