flumorph: Fungicides, Industrial; similar to dimethomorph [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
flumorph : A mixture comprising approximately equal amounts of (E)- and (Z)-fluomorph. It is used as an agrochemical fungicide for the control oomcyetes such as downey mildew on vegetables and grapes. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
(E)-flumorph : An enamide resulting from the formal condensation of (2E)-3-(4-fluorophenyl)-3-(3,4-dimethoxyphenyl)acrylic acid with the amino group of morpholine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 11057755 |
| CHEBI ID | 83428 |
| CHEBI ID | 83430 |
| SCHEMBL ID | 1389289 |
| MeSH ID | M0521237 |
| Synonym |
|---|
| ccris 9057 |
| flumorph |
| flumorph [iso] |
| 211867-47-9 |
| 4-(3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-oxo-2-propenyl)morpholine |
| unii-av4lx5ws5p |
| av4lx5ws5p , |
| HY-17521 |
| CS-3307 |
| (e)-flumorph |
| CHEBI:83428 |
| CHEBI:83430 |
| 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(morpholin-4-yl)prop-2-en-1-one |
| (2e)-3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-(morpholin-4-yl)prop-2-en-1-one |
| 3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-morpholinoprop-2-en-1-one |
| SCHEMBL1389289 |
| flumorph 100 microg/ml in acetonitrile |
| (e)-3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-morpholin-4-ylprop-2-en-1-one |
| Q19279669 |
| AMY3300 |
| cid 20056423 |
| 3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-morpholin-4-ylprop-2-en-1-one |
| morpholine,4-[3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-oxo-2-propenyl]- |
| AS-79577 |
| syp-l190syp-l190 |
| A879211 |
| syp-l190 |
Flumorph is an oomycete fungicide that is now used extensively in China. Little is known about its effect on nontarget soil organisms.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Flumorph is an Oomycete fungicide, which is used extensively as an effective fungicide in vegetables and fruits, but little is known about its effect on nontarget soil organisms. " | ( DNA damage and effects on antioxidative enzymes in earthworm (Eisenia fetida) induced by flumorph. Cai, L; Cao, X; Hui, X; Li, S; Liu, J; Tian, Y; Yang, C; Yang, W, 2014) | 2.07 |
| "Flumorph is an oomycete fungicide that is now used extensively in China. " | ( Degradation of flumorph in soils, aqueous buffer solutions, and natural waters. Hu, JY; Liu, C; Yan, H, 2008) | 2.14 |
| "Flumorph is an oomycete fungicide that is now used extensively in China (Hu, J. " | ( Photodegradation of flumorph in aqueous solutions and natural water under abiotic conditions. Hu, JY; Liu, C; Liu, CL; Qin, DM; Zhang, X, 2009) | 2.12 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, in the repeated 28-day oral toxicity study , flumorph was orally administered at doses 0, 30, 100, and 300 mg/kg/day for at least 28 days, a significantly increase in T(4) value in male rats and TSH value in female rats were detected in the highest dosage group, respectively." | ( Uterotrophic assay, Hershberger assay, and repeated 28-day oral toxicity study of flumorph based on the Organization for Economic Co-operation and Development draft protocols. Cai, L; Wang, J; Wu, Y; Yao, B; Zhang, L; Zhao, J, 2011) | 0.84 |
| Class | Description |
|---|---|
| aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
| morpholines | Any compound containing morpholine as part of its structure. |
| organofluorine compound | An organofluorine compound is a compound containing at least one carbon-fluorine bond. |
| tertiary carboxamide | A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR(1)R(2). |
| enamide | An alpha,beta-unsaturated carboxylic acid amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) in which the amide C=O function is conjugated to a C=C double bond at the alpha,beta position. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (30.15) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 13 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||