Page last updated: 2024-12-11
eupalmerin acetate
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
eupalmerin acetate: cyclic diterpenoid from gorgonians of the Eunicea genus; RN given refers to (1aR-(1aR*,4E,9S*,10R*,13aS*,14R*))-isomer; RN for cpd without isomeric designation not avail 9/93; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 5459169 |
| CHEMBL ID | 1986885 |
| MeSH ID | M0220001 |
Synonyms (5)
| Synonym |
|---|
| nsc-637469 |
| eupalmerin acetate |
| NSC637469 , |
| CHEMBL1986885 |
| [(1s,3r,5r,8e,13s,14r,15r)-5,9,13-trimethyl-18-methylidene-17-oxo-4,16-dioxatricyclo[13.3.0.03,5]octadec-8-en-14-yl] acetate |
Research Excerpts
Overview
Eupalmerin acetate (EPA) is a marine diterpene compound isolated from the gorgonian octocorals Eunicea succinea and E Unicea mammosa.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Eupalmerin acetate (EPA) is a marine diterpene compound isolated from the gorgonian octocorals Eunicea succinea and Eunicea mammosa. " | ( Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate. Akk, G; Eterović, VA; Evers, AS; Li, P; Manion, BD; Reichert, DE; Rodríguez, AD; Steinbach, JH, 2008) | 2.01 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " ACh dose-response curves suggested that his inhibition was noncompetitive." | ( Diterpenoids from Caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor. Eterović, VA; Ferchmin, PA; Hann, RM; Lee, YH; Li, L; McNamee, MG; Rodriguez, AD, 1993) | 0.29 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.24
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.24) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||