Compounds > emimycin
Page last updated: 2024-11-08

emimycin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID274093
CHEMBL ID4293219
SCHEMBL ID9593430
MeSH IDM0091463

Synonyms (21)

Synonym
1,2-dihydro-2-oxopyrazine 4-oxide
2(1h)-pyrazinone, 4-oxide
enimycin
emimycin
2(1h)pyrazinone 4-oxide
nsc-119867
2-hydroxypyrazine 4-oxide
nsc119867
3735-46-4
pyrazinol, 4-oxide
nsc 119867
4-oxido-1h-pyrazin-4-ium-2-one
4-oxido-1,3-dihydropyrazin-2-one
A823771
4-oxidanidyl-1h-pyrazin-4-ium-2-one
unii-r14te35lhd
r14te35lhd ,
SCHEMBL9593430
3-oxo-3,4-dihydropyrazine 1-oxide
Q27287646
CHEMBL4293219

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (9)

Assay IDTitleYearJournalArticle
AID1402817Antiviral activity against Influenza B virus B/Ned/537/05 infected in MDCK cells assessed as reduction in virus-induced cytopathic effect by MTS assay2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402821Cytotoxicity against human HeLa cells at 100 uM2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402820Antiviral activity against RSV infected in human HeLa cells at 100 uM2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402819Cytotoxicity against MDCK cells assessed as alteration in cell morphology by microscopic method2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402813Antibacterial activity against Escherichia coli2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402814Antibacterial activity against Streptococcus faecium2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402818Cytotoxicity against MDCK cells assessed as reduction in cell viability by MTS assay2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402815Antiviral activity against Influenza A virus A/Ned/378/05(H1N1) infected in MDCK cells assessed as reduction in virus-induced cytopathic effect by MTS assay2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
AID1402816Antiviral activity against Influenza A virus A/HK/7/87(H3N2) infected in MDCK cells assessed as reduction in virus-induced cytopathic effect by MTS assay2018European journal of medicinal chemistry, Jan-20, Volume: 144Emimycin and its nucleoside derivatives: Synthesis and antiviral activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 47.39

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index47.39 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index65.56 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (47.39)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
uracil
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder		1.9710pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
xanthine
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.. 9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.		1.9710xanthineSaccharomyces cerevisiae metabolite
floxuridine
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.. floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.		1.9710nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent
pyrazines
Pyrazines: A heterocyclic aromatic organic compound with the chemical formula C4H4N2.. pyrazine : A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms.		3.0650diazine;
pyrazines		Daphnia magna metabolite
cidofovir anhydrous
Cidofovir: An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.. cidofovir anhydrous : Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.		2.1710phosphonic acids;
pyrimidone		anti-HIV agent;
antineoplastic agent;
antiviral drug;
photosensitizing agent
brivudine
brivudine: anti-herpes agent		2.1710
acyclovir
Acyclovir: A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.. acyclovir : An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.		2.17102-aminopurines;
oxopurine		antimetabolite;
antiviral drug
ConditionIndicatedRelationship StrengthStudiesTrials
Herpes Simplex Virus Infection
[description not available]		02.1710
Congenital Varicella Syndrome
[description not available]		02.1710
Herpes Simplex
A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)		02.1710