Page last updated: 2024-11-13
communesin b
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
communesin B: from ethyl acetate extract of Penicillium sp., derived from the Mediterranean sponge Axinella verrucosa; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 44575539 |
| CHEMBL ID | 509067 |
| MeSH ID | M0463805 |
Synonyms (8)
| Synonym |
|---|
| communesin b |
| CHEMBL509067 |
| 148439-46-7 |
| Q15410926 |
| communesine b |
| DTXSID001017735 |
| 2,4-hexadien-1-one, 1-[(3ar,8ar,13br,16r,16as,17s)-17-[(2r)-3,3-dimethyl-2-oxiranyl]-2,3,8a,9,14,15-hexahydro-9-methyl-13,16-methano-8h,16h-pyrrolo[2',3':2,3]pyrido[4,3-o]quinindolin-1(16ah)-yl]-, (2e,4e)- |
| (2e,4e)-1-[(2s,6r,14r,22r,25s)-25-[(2r)-3,3-dimethyloxiran-2-yl]-15-methyl-1,3,13,15-tetrazaheptacyclo[18.4.1.02,6.06,22.07,12.014,22.016,21]pentacosa-7,9,11,16,18,20-hexaen-3-yl]hexa-2,4-dien-1-one |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (8)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID399251 | Toxicity in Artemia salina | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| AID399249 | Antiproliferative activity against human L428 cells after 48 hrs by MTT assay | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| AID399248 | Antiproliferative activity against human MOLT3 cells after 48 hrs by MTT assay | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| AID399246 | Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| AID399245 | Antiproliferative activity against human U937 cells after 48 hrs by MTT assay | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| AID399250 | Antiproliferative activity against human SUP-B15 cells after 48 hrs by MTT assay | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| AID1103160 | Insecticidal activity against po dosed third-instar larvae of Bombyx mori assessed as gram of diet | 2004 | Bioscience, biotechnology, and biochemistry, Mar, Volume: 68, Issue:3 | New insecticidal compounds, communesins C, D and E, from Penicillium expansum link MK-57. |
| AID399247 | Antiproliferative activity against human NAMALWA cells after 48 hrs by MTT assay | 2004 | Journal of natural products, Jan, Volume: 67, Issue:1 | New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (13)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (76.92) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 11.67
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.67) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (7.69%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (92.31%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||