bryonolic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

bryonolic acid: structure given in first source; an anti-allergy agent isolated from Luffa cylindrica, the roots of Bryonia dioica, and the fruit hulls of Sandrica indicum [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Flora	Rank	Flora Definition	Family	Family Definition
Bryonia	genus	A plant genus of the family CUCURBITACEAE that is the source of bryodin 1 (a ribosome-inactivating protein).[MeSH]	Cucurbitaceae	The gourd plant family of the order Violales, subclass Dilleniidae, class Magnoliopsida. It is sometimes placed in its own order, Cucurbitales. 'Melon' generally refers to CUCUMIS; CITRULLUS; or MOMORDICA.[MeSH]
Luffa	genus	A plant genus of the family CUCURBITACEAE known for the fruit which is the source of the luffa sponge and the seeds which contain luffin.[MeSH]	Cucurbitaceae	The gourd plant family of the order Violales, subclass Dilleniidae, class Magnoliopsida. It is sometimes placed in its own order, Cucurbitales. 'Melon' generally refers to CUCUMIS; CITRULLUS; or MOMORDICA.[MeSH]

Cross-References

ID Source	ID
PubMed CID	10253568
MeSH ID	M0202213

Synonyms (4)

Synonym
bryonolic acid
24480-45-3
(2r,4as,6as,12as,14as)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid
d:c-friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-; d:c-friedoolean-8-en-29-oic acid, 3beta-hydroxy-

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (15)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	5 (33.33)	18.2507
2000's	5 (33.33)	29.6817
2010's	4 (26.67)	24.3611
2020's	1 (6.67)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	15 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
benzoic acid Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.. benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.. aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.	2.05	1	benzoic acids	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
chloroform Chloroform: A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.. chloroform : A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.	2.01	1	chloromethanes; one-carbon compound	carcinogenic agent; central nervous system drug; inhalation anaesthetic; non-polar solvent; refrigerant
oleanolic acid [no description available]	2.07	1	hydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
n-methylaspartate N-Methylaspartate: An amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors (RECEPTORS, NMDA).. N-methyl-D-aspartic acid : An aspartic acid derivative having an N-methyl substituent and D-configuration.	2.13	1	amino dicarboxylic acid; D-alpha-amino acid; D-aspartic acid derivative; secondary amino compound	neurotransmitter agent
deuterium Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.	2.01	1	dihydrogen
glycosides [no description available]	2.05	1
cucurbitacin b [no description available]	2.73	3	cucurbitacin; secondary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone
cucurbitacin c cucurbitacin C: structure in first source	2.05	1	cucurbitacin
cucurbitacin d cucurbitacin D: toxic constituent in edible gourd; see also records for cucurbitacins & specific cucurbitacins. cucurbitacin D : A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23.	2.05	1	cucurbitacin; secondary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone
cucurbitane cucurbitane: structure in first source. cucurbitane : A triterpene that is an isomer of lanostane obtained by migration of the methyl group from 10 to the 9beta position.	2.05	1	triterpene

Condition	Relationship Strength	Studies
Cerebral Ischemia [description not available]	2.13	1
Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.	2.13	1
Breast Cancer [description not available]	2.05	1
Cancer of Colon [description not available]	2.05	1
Cancer of Lung [description not available]	2.05	1
Breast Neoplasms Tumors or cancer of the human BREAST.	2.05	1
Colonic Neoplasms Tumors or cancer of the COLON.	2.05	1
Lung Neoplasms Tumors or cancer of the LUNG.	2.05	1
Cancer of the Uterus [description not available]	1.98	1
Choriocarcinoma A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).	1.98	1
Uterine Neoplasms Tumors or cancer of the UTERUS.	1.98	1
B16 Melanoma [description not available]	1.98	1
Arthus Phenomenon [description not available]	1.98	1
Asthma, Bronchial [description not available]	1.98	1
Allergic Reaction [description not available]	1.98	1
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	1.98	1
Dermatitis Any inflammation of the skin.	1.98	1
Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.	1.98	1
Delayed Hypersensitivity [description not available]	1.97	1

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