Page last updated: 2024-11-13

aszonalenin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

aszonalenin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID42636439
CHEBI ID192681
MeSH IDM000611177

Synonyms (17)

Synonym
81797-27-5
aszonalenin
nsc-374337
CHEBI:192681
(2r,3s,11r)-aszonalenin
(2r,3s,11r)-aszonalenin zwitterion
aszonalenine
aszonalenine, (+)-
(5ar,13ar,14as)-14a-(1,1-dimethyl-2-propenyl)-5a,13a,14,14a-tetrahydroindolo(3',2':4,5)pyrrolo(2,1-c)(1,4)benzodiazepine-7,13(5h,12h)-dione
indolo(3',2':4,5)pyrrolo(2,1-c)(1,4)benzodiazepine-7,13(5h,12h)-dione, 14a-(1,1-dimethyl-2-propenyl)-5a,13a,14,14a-tetrahydro-, (5ar,13ar,14as)-
0v5dq674au ,
indolo(3',2':4,5)pyrrolo(2,1-c)(1,4)benzodiazepine-7,13(5h,12h)-dione, 14a-(1,1-dimethyl-2-propenyl)-5a,13a,14,14a-tetrahydro-, (5ar-(5aalpha,13abeta,14aalpha))-
unii-0v5dq674au
indolo(3',2':4,5)pyrrolo(2,1-c)(1,4)benzodiazepine-7,13(5h,12h)-dione, 14a-(1,1-dimethyl-2-propenyl)-5a,13a,14,14a-tetrahydro-, (5ar-(5a.alpha.,13a.beta.,14a.alpha.))-
[5ar,(+)]-14abeta-(1,1-dimethyl-2-propenyl)-5abeta,13aalpha,14,14a-tetrahydroindolo[3',2'
HY-123006
CS-0079843

Research Excerpts

Overview

Epi-aszonalenin A (EAA) is an alkaloid that is isolated and purified from the secondary metabolites of coral symbiotic fungi. EAA has been shown to have good atherosclerotic intervention activity and anti-angiogenic activity.

ExcerptReferenceRelevance
"Epi-aszonalenin A (EAA) is an alkaloid that is isolated and purified from the secondary metabolites of coral symbiotic fungi and has been shown to have good atherosclerotic intervention activity and anti-angiogenic activity in our previous studies. "( Mechanisms of Antitumor Invasion and Metastasis of the Marine Fungal Derivative Epi-Aszonalenin A in HT1080 Cells.
He, YL; Hong, P; Li, Y; Lin, L; Liu, Y; Qian, ZJ; Sun, S; Zhang, Y; Zheng, H; Zhou, C, 2023
)
1.69
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
benzodiazepineA group of heterocyclic compounds with a core structure containing a benzene ring fused to a diazepine ring.
zwitterionA neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.92

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.92 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.71 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.92)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]