Page last updated: 2024-11-07
6-bromoisatin
Description
6-Bromoisatin is a synthetically modified derivative of isatin. Its synthesis typically involves bromination of isatin using bromine in a suitable solvent. 6-Bromoisatin has been studied for its biological activities, including its potential as a therapeutic agent for various diseases. It has shown promising effects as an anticancer agent, exhibiting cytotoxicity against different cancer cell lines. The compound has also been investigated for its anti-inflammatory and antimicrobial properties. Its importance lies in its potential for drug discovery and development, especially in the areas of cancer therapy and infectious diseases. 6-Bromoisatin is a valuable tool for researchers exploring the structure-activity relationships of isatin derivatives and their therapeutic applications.'
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6-bromoisatin: anticancer compound from Dicathais orbita; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 95716 |
| CHEMBL ID | 223335 |
| SCHEMBL ID | 8557 |
| MeSH ID | M0574812 |
Synonyms (36)
| Synonym |
|---|
| AC-3241 |
| 6-bromo-2,3-dihydro-1h-indole-2,3-dione |
| EN300-24656 |
| BB 0255184 |
| nsc-30748 |
| nsc30748 |
| 6326-79-0 |
| 6-bromo-isatin |
| 6-bromoisatin |
| STK399865 |
| 6-bromo-1h-indole-2,3-dione |
| 6-bromo-2,3-indolinedione |
| B2424 |
| 6-bromoindole-2,3-dione |
| CHEMBL223335 |
| FT-0660878 |
| AKOS000119280 |
| nsc 30748 |
| 1h-indole-2,3-dione, 6-bromo- |
| 6-bromoindoline-2,3-dione |
| FT-0649291 |
| AM20061106 |
| HVPQMLZLINVIHW-UHFFFAOYSA-N |
| SCHEMBL8557 |
| SY004824 |
| mfcd01631138 |
| FS-3757 |
| Q-200552 |
| DTXSID50212651 |
| 6-bromo-1h-indole-2,3-dione, aldrichcpr |
| 6-bromo isatin |
| CS-W002793 |
| UVA4QW7PH2 |
| SB40596 |
| CDA60345 |
| Z199464140 |
Research Excerpts
Toxicity
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 22.09
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 22.09 (24.57) | | Research Supply Index | 1.95 (2.92) | | Research Growth Index | 4.73 (4.65) | | Search Engine Demand Index | 18.60 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |