Assay ID | Title | Year | Journal | Article |
AID1461889 | Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 24 hrs by alamar blue assay | | | |
AID1298193 | Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assay | 2016 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 26, Issue:11
| Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening. |
AID463364 | Antiproliferative activity against human RS4:11 cells having FLT3-ITD mutation after 72 hrs by WST8 assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 20, Issue:6
| Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. |
AID532592 | Therapeutic index, ration of TD50 for human foreskin fibroblast cell infected with Toxoplasma gondii to ID 50 for Toxoplasma gondii | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12
| Inhibition of Toxoplasma gondii by indirubin and tryptanthrin analogs. |
AID532590 | Cytotoxicity against human foreskin fibroblast cell infected with Toxoplasma gondii | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12
| Inhibition of Toxoplasma gondii by indirubin and tryptanthrin analogs. |
AID463363 | Antiproliferative activity against wild type FLT3 expressing human MV411 cells after 72 hrs by WST8 assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 20, Issue:6
| Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. |
AID73206 | Inhibition of glycogen synthase kinase-3-alpha/beta (GSK-3-alpha/beta) in porcine brain relative to indirubin | 2004 | Journal of medicinal chemistry, Feb-12, Volume: 47, Issue:4
| Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases. |
AID532591 | Antimicrobial activity against Toxoplasma gondii | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12
| Inhibition of Toxoplasma gondii by indirubin and tryptanthrin analogs. |
AID463365 | Inhibition of FLT3 by HTRF assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 20, Issue:6
| Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |