Compounds > 5'-iodoindirubin
Page last updated: 2024-09-03

5'-iodoindirubin and 6-bromoindirubin-3'-oxime

5'-iodoindirubin has been researched along with 6-bromoindirubin-3'-oxime in 2 studies

Compound Research Comparison

Studies
(5'-iodoindirubin)		Trials
(5'-iodoindirubin)		Recent Studies (post-2010)
(5'-iodoindirubin)		Studies
(6-bromoindirubin-3'-oxime)		Trials
(6-bromoindirubin-3'-oxime)		Recent Studies (post-2010) (6-bromoindirubin-3'-oxime)
6011710114

Protein Interaction Comparison

ProteinTaxonomy5'-iodoindirubin (IC50)6-bromoindirubin-3'-oxime (IC50)
SUMO1/sentrin specific peptidase 7Homo sapiens (human)5.6
Glycogen synthase kinase-3 beta Sus scrofa (pig)0.005
[Tau protein] kinase Sus scrofa (pig)0.005
caspase-3 isoform a preproproteinHomo sapiens (human)64.3
matrix metalloproteinase-14 preproproteinHomo sapiens (human)5.335
melanocortin receptor 4Homo sapiens (human)6.37
Aurora kinase AHomo sapiens (human)0.6
Casein kinase I isoform alphaSus scrofa (pig)1.2
Cyclin-T1Homo sapiens (human)0.45
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.32
Cyclin-dependent kinase 1Homo sapiens (human)0.3117
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)2.0333
Cyclin-dependent kinase 4Homo sapiens (human)0.527
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.3075
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)0.6
Cyclin-A2Homo sapiens (human)0.069
G1/S-specific cyclin-D1Homo sapiens (human)0.527
G1/S-specific cyclin-E1Homo sapiens (human)0.014
Cyclin-dependent kinase 2Homo sapiens (human)0.0415
Dual specificity protein kinase CLK1Homo sapiens (human)2.1
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.062
Glycogen synthase kinase-3 betaHomo sapiens (human)0.3298
Cyclin-dependent kinase 7Homo sapiens (human)3.5
Cyclin-dependent kinase 9Homo sapiens (human)0.45
Cyclin-HHomo sapiens (human)3.5
CDK-activating kinase assembly factor MAT1Homo sapiens (human)3.5
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.078
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.052
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.0746
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrialHomo sapiens (human)1.5
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)1.11
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.32
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)2.1
Aurora kinase BHomo sapiens (human)0.9
Bile acid receptorHomo sapiens (human)3.4
Aurora kinase CHomo sapiens (human)0.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greengard, P; Leost, M; Magiatis, P; Meijer, L; Mikros, E; Musacchio, A; Myrianthopoulos, V; Pearl, L; Polychronopoulos, P; Roe, SM; Skaltsounis, AL; Tarricone, A1
Grundt, P; Jones-Brando, L; Krivogorsky, B; Yolken, R1

Other Studies

2 other study(ies) available for 5'-iodoindirubin and 6-bromoindirubin-3'-oxime

ArticleYear
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3; Indoles; Models, Molecular; Oximes; Structure-Activity Relationship

2004
Inhibition of Toxoplasma gondii by indirubin and tryptanthrin analogs.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12

    Topics: Animals; Antiprotozoal Agents; Drugs, Chinese Herbal; Indoles; Isatis; Parasitic Sensitivity Tests; Quinazolines; Toxoplasma

2008