5'-iodoindirubin has been researched along with indirubin in 4 studies
| Studies (5'-iodoindirubin) | Trials (5'-iodoindirubin) | Recent Studies (post-2010) (5'-iodoindirubin) | Studies (indirubin) | Trials (indirubin) | Recent Studies (post-2010) (indirubin) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 347 | 3 | 184 |
| Protein | Taxonomy | 5'-iodoindirubin (IC50) | indirubin (IC50) |
|---|---|---|---|
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | 1 | |
| [Tau protein] kinase | Sus scrofa (pig) | 1 | |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | 2.2 | |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | 8.25 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 2 | |
| Insulin receptor | Homo sapiens (human) | 2 | |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 7.74 | |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | 2.2 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 8.8333 | |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | 1 | |
| Cyclin-A2 | Homo sapiens (human) | 3.525 | |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | 2.2 | |
| Kit ligand | Homo sapiens (human) | 2 | |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | 4.85 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 3.24 | |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | 2 | |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | 2.2 | |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | 1.5 | |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | 0.8515 | |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | 6.15 | |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | 6.7143 | |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 20 | Homo sapiens (human) | 2.2 | |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | 8.25 | |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | 2.2 | |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | 1 | |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | 2.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greengard, P; Leost, M; Magiatis, P; Meijer, L; Mikros, E; Musacchio, A; Myrianthopoulos, V; Pearl, L; Polychronopoulos, P; Roe, SM; Skaltsounis, AL; Tarricone, A | 1 |
| Grundt, P; Jones-Brando, L; Krivogorsky, B; Yolken, R | 1 |
| Choi, SJ; Choi, SU; Han, SY; Kim, YC; Lee, SD; Moon, MJ | 1 |
| Byun, BJ; Choi, G; Choi, SU; Jung, ME; Kim, HM; Kim, SJ; Kim, YC; Lee, JY; Lee, K; Lee, N; Park, JH; Son, YH; Yang, KM | 1 |
4 other study(ies) available for 5'-iodoindirubin and indirubin
| Article | Year |
|---|---|
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
Topics: Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3; Indoles; Models, Molecular; Oximes; Structure-Activity Relationship | 2004 |
Inhibition of Toxoplasma gondii by indirubin and tryptanthrin analogs.
Topics: Animals; Antiprotozoal Agents; Drugs, Chinese Herbal; Indoles; Isatis; Parasitic Sensitivity Tests; Quinazolines; Toxoplasma | 2008 |
Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Humans; Indoles; Leukemia, Myeloid, Acute | 2010 |
Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.
Topics: Apoptosis Regulatory Proteins; Dose-Response Relationship, Drug; Drug Discovery; High-Throughput Screening Assays; Humans; Indoles; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Structure-Activity Relationship | 2016 |