2',3'-cyclic gmp

Description

2',3'-cyclic GMP: was GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93; use CYCLIC GMP to search 1980-93 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2',3'-cyclic GMP : A 2',3'-cyclic purine nucleotide in which guanosine is used as the parent nucleoside. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	135398728
CHEBI ID	28181
SCHEMBL ID	4063650
MeSH ID	M0209617

Synonyms (32)

Synonym
guanosine cyclic-2',3'-monophosphate
CHEBI:28181
cyclic guanosine 2',3'-monophosphate
o(2'),o(3')-hydroxyphosphoryl-guanosine
guanosine cyclic 2',3'-(hydrogen phosphate)
guanosine 2',3'-cyclic phosphate
2',3'-cyclic gmp
C06194 ,
guanosine 2',3'-cyclic monophosphate
34DF8A42-40BB-441B-A058-8E0008232C94
guanosine-2',3'-cyclic-monophosphate
634-02-6
2-amino-9-[(3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-1,9-dihydro-6h-purin-6-one
9-[(3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-2-amino-3h-purin-6-one
15718-49-7
vgu8zu3am5 ,
unii-vgu8zu3am5
einecs 211-203-0
SCHEMBL4063650
2',3'-cgmp
9-[(3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxo-tetrahydro-2h-1,3,5,2$l^{5}-furo[3,4-d][1,3,2$l^{5}]dioxaphosphol-4-yl]-2-amino-6,9-dihydro-3h-purin-6-one
cyclic 2',3'-(hydrogen phosphate)-guanosine
2',3' cgmp
9k9 ,
2-amino-9-[(2s,3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxotetrahydro-2h-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]-3,9-dihydro-6h-purin-6-one
23G ,
Q27103546
DTXSID80979568
2-hydroxy-4-(6-hydroxy-2-imino-2,3-dihydro-9h-purin-9-yl)-6-(hydroxymethyl)tetrahydro-2h-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-2-one
9-((3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxo-3a,4,6,6a-tetrahydrofuro(3,4-d)(1,3,2)dioxaphosphol-4-yl)-2-amino-1h-purin-6-one
guanosine cyclic 2',3'-phosphate
2',3'-cyclic guanylic acid

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

Role	Description
Escherichia coli metabolite	Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

Class	Description
2',3'-cyclic purine nucleotide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (18.18)	18.2507
2000's	3 (27.27)	29.6817
2010's	4 (36.36)	24.3611
2020's	2 (18.18)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	11 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
histidine Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.	1.99	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
lutetium Lutetium: An element of the rare earth family of metals. It has the atomic symbol Lu, atomic number 71, and atomic weight 175.	2	1	d-block element atom; lanthanoid atom
2',3'-cyclic amp 2',3'-cyclic AMP: structure; ADENOSINE CYCLIC 2',3'-MONOPHOSPHATE was see ADENOSINE CYCLIC MONOPHOSPHATE 1980-93; use CYCLIC AMP to search ADENOSINE CYCLIC 2',3'-MONOPHOSPHATE 1980-93	2.21	1	2',3'-cyclic purine nucleotide	Escherichia coli metabolite
lignin Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed). lignin : A polyphenylpropanoid derived from three monolignol monomers: trans-p-coumaryl alcohol, coniferol and trans-sinapyl alcohol. There is extensive cross-linking and no defined primary structure.	2.21	1
alpha-sarcin alpha-sarcin: basic protein 150 aa, MW 16 kDa; isolated from aspergillus giganteus; sequence similarity with ribonucleases such as RIBONUCLEASE T1; 85% identity with restrictocin; a ribotoxin cleaving the phosphodiester bond on the 3' side of G4325 in the alpha-sarcin/ricin domain of rat 28S RIBOSOMAL RNA; sometimes called a ribosome-inactivating protein but falls outside the normal definition of plant RIP that de-adenylate rRNA	1.99	1
cellulose DEAE-Cellulose: Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.	2.21	1	glycoside
cyclic gmp Cyclic GMP: Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed). 3',5'-cyclic GMP : A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine.	2.21	1	3',5'-cyclic purine nucleotide; guanyl ribonucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
guanosine ribonucleoside : Any nucleoside where the sugar component is D-ribose.	2.21	1	guanosines; purines D-ribonucleoside	fundamental metabolite
bis(3',5')-cyclic diguanylic acid [no description available]	2.21	1	cyclic purine dinucleotide; guanyl ribonucleotide	immunomodulator; signalling molecule

Condition	Relationship Strength	Studies
Asthma, Bronchial [description not available]	2.31	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.31	1
Eosinophilia, Tropical [description not available]	2.31	1
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	2.31	1
Eosinophilia Abnormal increase of EOSINOPHILS in the blood, tissues or organs.	2.31	1
Abnormalities, Autosome [description not available]	1.98	1

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