Compounds > 2',3'-cyclic gmp
Page last updated: 2024-10-15

2',3'-cyclic gmp

Description

2',3'-cyclic GMP: was GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93; use CYCLIC GMP to search 1980-93 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2',3'-cyclic GMP : A 2',3'-cyclic purine nucleotide in which guanosine is used as the parent nucleoside. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID135398728
CHEBI ID28181
SCHEMBL ID4063650
MeSH IDM0209617

Synonyms (32)

Synonym
guanosine cyclic-2',3'-monophosphate
CHEBI:28181
cyclic guanosine 2',3'-monophosphate
o(2'),o(3')-hydroxyphosphoryl-guanosine
guanosine cyclic 2',3'-(hydrogen phosphate)
guanosine 2',3'-cyclic phosphate
2',3'-cyclic gmp
C06194 ,
guanosine 2',3'-cyclic monophosphate
34DF8A42-40BB-441B-A058-8E0008232C94
guanosine-2',3'-cyclic-monophosphate
634-02-6
2-amino-9-[(3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-1,9-dihydro-6h-purin-6-one
9-[(3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-2-amino-3h-purin-6-one
15718-49-7
vgu8zu3am5 ,
unii-vgu8zu3am5
einecs 211-203-0
SCHEMBL4063650
2',3'-cgmp
9-[(3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxo-tetrahydro-2h-1,3,5,2$l^{5}-furo[3,4-d][1,3,2$l^{5}]dioxaphosphol-4-yl]-2-amino-6,9-dihydro-3h-purin-6-one
cyclic 2',3'-(hydrogen phosphate)-guanosine
2',3' cgmp
9k9 ,
2-amino-9-[(2s,3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxotetrahydro-2h-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]-3,9-dihydro-6h-purin-6-one
23G ,
Q27103546
DTXSID80979568
2-hydroxy-4-(6-hydroxy-2-imino-2,3-dihydro-9h-purin-9-yl)-6-(hydroxymethyl)tetrahydro-2h-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-2-one
9-((3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxo-3a,4,6,6a-tetrahydrofuro(3,4-d)(1,3,2)dioxaphosphol-4-yl)-2-amino-1h-purin-6-one
guanosine cyclic 2',3'-phosphate
2',3'-cyclic guanylic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
Escherichia coli metaboliteAny bacterial metabolite produced during a metabolic reaction in Escherichia coli.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
2',3'-cyclic purine nucleotide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's2 (18.18)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
histidine
Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.		1.9910amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
lutetium
Lutetium: An element of the rare earth family of metals. It has the atomic symbol Lu, atomic number 71, and atomic weight 175.		210d-block element atom;
lanthanoid atom
2',3'-cyclic amp
2',3'-cyclic AMP: structure; ADENOSINE CYCLIC 2',3'-MONOPHOSPHATE was see ADENOSINE CYCLIC MONOPHOSPHATE 1980-93; use CYCLIC AMP to search ADENOSINE CYCLIC 2',3'-MONOPHOSPHATE 1980-93		2.21102',3'-cyclic purine nucleotideEscherichia coli metabolite
lignin
Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed). lignin : A polyphenylpropanoid derived from three monolignol monomers: trans-p-coumaryl alcohol, coniferol and trans-sinapyl alcohol. There is extensive cross-linking and no defined primary structure.		2.2110
alpha-sarcin
alpha-sarcin: basic protein 150 aa, MW 16 kDa; isolated from aspergillus giganteus; sequence similarity with ribonucleases such as RIBONUCLEASE T1; 85% identity with restrictocin; a ribotoxin cleaving the phosphodiester bond on the 3' side of G4325 in the alpha-sarcin/ricin domain of rat 28S RIBOSOMAL RNA; sometimes called a ribosome-inactivating protein but falls outside the normal definition of plant RIP that de-adenylate rRNA		1.9910
cellulose
DEAE-Cellulose: Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.		2.2110glycoside
cyclic gmp
Cyclic GMP: Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed). 3',5'-cyclic GMP : A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine.		2.21103',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
guanosine
ribonucleoside : Any nucleoside where the sugar component is D-ribose.		2.2110guanosines;
purines D-ribonucleoside		fundamental metabolite
bis(3',5')-cyclic diguanylic acid
[no description available]		2.2110cyclic purine dinucleotide;
guanyl ribonucleotide		immunomodulator;
signalling molecule
ConditionIndicatedRelationship StrengthStudiesTrials
Asthma, Bronchial
[description not available]		02.3110
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.3110
Eosinophilia, Tropical
[description not available]		02.3110
Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).		02.3110
Eosinophilia
Abnormal increase of EOSINOPHILS in the blood, tissues or organs.		02.3110
Abnormalities, Autosome
[description not available]		01.9810