Page last updated: 2024-09-05
tau 284 and doxepin
tau 284 has been researched along with doxepin in 1 studies
Compound Research Comparison
| Studies (tau 284) | Trials (tau 284) | Recent Studies (post-2010) (tau 284) | Studies (doxepin) | Trials (doxepin) | Recent Studies (post-2010) (doxepin) |
|---|---|---|---|---|---|
| 52 | 18 | 21 | 885 | 207 | 129 |
Protein Interaction Comparison
| Protein | Taxonomy | tau 284 (IC50) | doxepin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.046 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.029 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.258 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.042 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.2 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.026 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.6675 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.077 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.2 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0355 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.5145 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.8595 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.069 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.688 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.029 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.867 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.118 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.038 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.046 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.8595 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.2 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.042 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.2 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0006 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.393 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.089 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 1.6 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.32 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.631 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.2 |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Duan, X; Funaki, Y; Ishikawa, Y; Itoh, M; Iwata, R; Kato, M; Miyake, M; Tashiro, M; Watanuki, S; Yanai, K | 1 |
Trials
1 trial(s) available for tau 284 and doxepin
| Article | Year |
|---|---|
Brain histamine H1 receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with 11C-doxepin.
Topics: Administration, Oral; Adult; Brain; Carbon Radioisotopes; Diphenhydramine; Doxepin; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperidines; Positron-Emission Tomography; Pyridines; Receptors, Histamine H1; Sleep Stages | 2008 |