Page last updated: 2024-09-04

cyc 202 and tretinoin

cyc 202 has been researched along with tretinoin in 10 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(tretinoin)
Trials
(tretinoin)
Recent Studies (post-2010) (tretinoin)
979739323,6541,0836,085

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)tretinoin (IC50)
Bile salt export pumpHomo sapiens (human)10
Amyloid-beta precursor proteinHomo sapiens (human)0.18
Adenosine receptor A3Homo sapiens (human)5.275
Retinoic acid receptor alphaHomo sapiens (human)2.2542
60 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Retinoic acid receptor betaHomo sapiens (human)0.7537
Retinoic acid receptor alphaMus musculus (house mouse)0.0057
Retinoic acid receptor gamma Homo sapiens (human)0.0064
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor gammaMus musculus (house mouse)0.004
Retinoic acid receptor betaMus musculus (house mouse)0.005
Mitogen-activated protein kinase 1Homo sapiens (human)0.576
Nuclear receptor ROR-alphaHomo sapiens (human)0.1995
Alpha-synucleinHomo sapiens (human)3
Cellular retinoic acid-binding protein 1Gallus gallus (chicken)0.5233
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.358
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor RXR-gammaHomo sapiens (human)0.35
Nuclear receptor ROR-gammaHomo sapiens (human)0.1995
10 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)0.82
60 kDa chaperonin Escherichia coli6.7
10 kDa chaperonin Escherichia coli6.7
Nuclear receptor ROR-betaHomo sapiens (human)0.1259

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bäckström, A; Cowburn, RF; Hasslund, K; Jämsä, A; Vasänge, M1
Díez, C; Gomez, E; Goyache, F; Gutiérrez-Adán, A; José Royo, L; Morán, E; Moreira, PN; Néstor Caamaño, J; Rodríguez, A1
Chen, MC; Chiang, MC; Hsu, FN; Kuo, HS; Lin, H; Lo, MJ; You, SC1
Feelders, RA; Hofland, LJ; Lacroix, A; Newell-Price, J; Nieman, LK; Pivonello, R1
Reincke, M; Theodoropoulou, M1
Duan, X; Gao, F; Rashid, A; Yang, M; Yen, A1

Reviews

2 review(s) available for cyc 202 and tretinoin

ArticleYear
Advances in the medical treatment of Cushing's syndrome.
    The lancet. Diabetes & endocrinology, 2019, Volume: 7, Issue:4

    Topics: ACTH Syndrome, Ectopic; ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenal Gland Neoplasms; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cabergoline; Cushing Syndrome; Dopamine Agonists; ErbB Receptors; Gefitinib; Hormones; Humans; Imidazoles; Isoquinolines; Molecular Targeted Therapy; Pituitary ACTH Hypersecretion; Pyrazoles; Pyridines; Receptors, Glucocorticoid; Roscovitine; Somatostatin; Temozolomide; Tretinoin

2019
Tumor-Directed Therapeutic Targets in Cushing Disease.
    The Journal of clinical endocrinology and metabolism, 2019, 03-01, Volume: 104, Issue:3

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Agents; Cabergoline; Clinical Trials as Topic; Corticotrophs; Humans; Pituitary ACTH Hypersecretion; Roscovitine; Silybin; Somatostatin; Treatment Outcome; Tretinoin

2019

Other Studies

8 other study(ies) available for cyc 202 and tretinoin

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The retinoic acid and brain-derived neurotrophic factor differentiated SH-SY5Y cell line as a model for Alzheimer's disease-like tau phosphorylation.
    Biochemical and biophysical research communications, 2004, Jul-02, Volume: 319, Issue:3

    Topics: Alzheimer Disease; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line, Tumor; Cell Size; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Neurofibrillary Tangles; Phosphorylation; Purines; Roscovitine; Serine; tau Proteins; Tretinoin

2004
Retinoid-dependent mRNA expression and poly-(A) contents in bovine oocytes meiotically arrested and/or matured in vitro.
    Molecular reproduction and development, 2004, Volume: 69, Issue:1

    Topics: Animals; Cattle; Cyclin-Dependent Kinases; Gene Expression Regulation, Developmental; Glucosephosphate Dehydrogenase; In Vitro Techniques; Meiosis; Oocytes; Protein Kinase Inhibitors; Purines; RNA, Messenger; Roscovitine; Superoxide Dismutase; Tretinoin

2004
The role of Cdk5 in retinoic acid-induced apoptosis of cervical cancer cell line.
    The Chinese journal of physiology, 2009, Feb-28, Volume: 52, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Survival; Cyclin-Dependent Kinase 5; Female; G1 Phase; Growth Inhibitors; HeLa Cells; Humans; Purines; RNA, Small Interfering; Roscovitine; Tretinoin; Uterine Cervical Neoplasms

2009
Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor.
    Cellular signalling, 2020, Volume: 71

    Topics: Cell Cycle Checkpoints; Cell Differentiation; Cell Proliferation; Down-Regulation; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Myeloid Cells; NADPH Oxidases; Phosphorylation; Principal Component Analysis; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins c-vav; Respiratory Burst; Roscovitine; Signal Transduction; src-Family Kinases; Tretinoin; Up-Regulation

2020