Page last updated: 2024-12-06
verofylline
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 47845 |
| CHEMBL ID | 2105599 |
| SCHEMBL ID | 636856 |
| MeSH ID | M0095588 |
Synonyms (29)
| Synonym |
|---|
| 65029-11-0 |
| 1,8-dimethyl-3-(2-methyl-1-butyl)xanthine |
| 3,7-dihydro-1,8-dimethyl-3-(2-methylbutyl)-1h-purine-2,6-dione |
| 1h-purine-2,6-dione, 3,7-dihydro-1,8-dimethyl-3-(2-methylbutyl)- |
| verofylline (usan/inn) |
| D06291 |
| 66172-75-6 |
| verofylline |
| ck-0383 |
| 1,8-dimethyl-3-(2-methylbutyl)-7h-purine-2,6-dione |
| CHEMBL2105599 |
| verofylline [usan:inn] |
| (r,s)-1,2,3,6-tetrahydro-1,8-dimethyl-3-(2-(methylbutyl)-2,6-purindion |
| verofyllinum [inn-latin] |
| ck 0383 |
| unii-1j8o1gt31u |
| verofilina |
| verofyllinum |
| (+-)-1,8-dimethyl-3-(2-methybutyl)xanthine |
| verofilina [inn-spanish] |
| 1h-purine-2,6-dione, 3,7-dihydro-1,8-dimethyl-3-(2-methylbutyl)-, (+-)- |
| 1j8o1gt31u , |
| verofylline [inn] |
| verofylline [usan] |
| SCHEMBL636856 |
| 1,8-dimethyl-3-(2-methylbutyl)-3,7-dihydro-1h-purine-2,6-dione |
| Q27252489 |
| DTXSID30867209 |
| AKOS040754349 |
Research Excerpts
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|---|---|
| " Since Cl and Vss increased similarly, the half-life of verofylline in obese rats did not change." | ( Verofylline pharmacokinetics in dietary-induced obese rats: role of fat mass and protein binding in determining volume of distribution. Jusko, WJ; Shum, L, 1991) | 1.97 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " Peak expiratory flow, forced vital capacity, and its subdivisions were measured weekly 2, 4, and 6 hr after oral dosing with drug or placebo." | ( Verofylline, a methylxanthine bronchodilator, in asthma. Booker, WM; Lucas, SG; Malveaux, FJ; Morris, EA; Pittman, J; Rachal, RE; Young, RC, 1984) | 1.71 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 42.34
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (42.34) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 3 (50.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 3 (50.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||