Compounds > styromal
Page last updated: 2024-12-06

styromal

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Styromal: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID62707
SCHEMBL ID16058
MeSH IDM0085404

Synonyms (52)

Synonym
nsc124032
nsc-124032
nsc137654
nsc-137654
sma 1440-h resin
styromal
sma 2000a
sma 1420al
malon ms 20
sma 2625a
sma 1000
styrene-maleic anhydride resin
lytron 820
sma 3000a
styrene maleic anhydride, resin
styromal 5
lytron 810
nsc99620
sma 17352a
dylark 230
styromal 30
povimal st
lytron 822
dylark 231
nsc-99620
dylark 232
sma 4000a
styrite hs 2
arco-sma 1000a
resin, sma 1440-h
9011-13-6
lpa 39
sma 1440h
sma 1000a
sma 2000
sma 1725a
sma 3000
42912-79-8
25736-61-2
AKOS015889038
WOLATMHLPFJRGC-UHFFFAOYSA-N
styrene maleic acid anhydride
maleic anhydride styrene
styrene maleic anhydride
styrene/maleic anhydride
SCHEMBL16058
maleic anhydride-styrene
mfcd00134011
DTXSID50911339
furan-2,5-dione--ethenylbenzene (1/1)
109768-17-4
furan-2,5-dione;styrene

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Hence, it is concluded that the polymer SMA injected at above doses appears to be safe in our experiment."( Preclinical toxicity study of a male injectable antifertility agent (styrene maleic anhydride) in rhesus monkeys, Macaca mulatta.
Nath, D; Sethi, N; Singh, RK; Srivastava, RK, 1991)		0.28
" Hence, the polymer is safe at the doses used within 6 months of injection."( Long-term toxicity studies of styrene maleic anhydride in rats.
Nath, D; Sethi, N; Singh, RK; Srivastava, RK, 1990)		0.28
" The results suggest the polymer SMA to be safe up to 5 times CD in monkeys."( Chronic toxicity of styrene maleic anhydride, a male contraceptive, in rhesus monkeys (Macaca mulatta).
Bhatia, GS; Sethi, N; Singh, RK; Sinha, N; Srivastava, RK, 1990)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (27)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (14.81)18.7374
1990's14 (51.85)18.2507
2000's3 (11.11)29.6817
2010's5 (18.52)24.3611
2020's1 (3.70)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.15

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.15 (24.57)
Research Supply Index3.40 (2.92)
Research Growth Index4.91 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.15)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (3.57%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other27 (96.43%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
dimethyl sulfoxide
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.		2.730sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
ethylenediamine
ethylenediamine: RN given refers to parent cpd; edamine is the recommended contraction for the ethylenediamine radical. ethylenediamine : An alkane-alpha,omega-diamine in which the alkane is ethane.		1.9710alkane-alpha,omega-diamineGABA agonist
triiodothyronine
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.. 3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.		1.97102-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
maleic anhydride
Maleic Anhydrides: Used in copolymerization reactions, in the Diels-Alder(diene)synthesis, in the preparation of resins, pharmaceuticals and agricultural chemicals. It is a powerful irritant and causes burns.. maleic anhydride : A cyclic dicarboxylic anhydride that is the cyclic anhydride of maleic acid.		6.02271cyclic dicarboxylic anhydride;
furans		allergen
1-octadecene
octadec-1-ene : An octadecene with unsaturation at C-1.. octadecene : An alkene that is octadecane containing one double bond at unspecified position.		2.0210octadecene
n-isopropylacrylamide
N-isopropylacrylamide: can polymerize with glycidyl acrylate to form reactive water-soluble polymer that can react with the amino groups of enzymes-proteins or other ligands		2.1710
alkenes
[no description available]		2.0210
tyrosyl-isoleucyl-glycyl-seryl-arginine
tyrosyl-isoleucyl-glycyl-seryl-arginine: a synthetic laminin pentapeptide		210
sodium bicarbonate
Sodium Bicarbonate: A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.		1.9910one-carbon compound;
organic sodium salt		antacid;
food anticaking agent
cufe2o4
[no description available]		2.0510
ConditionIndicatedRelationship StrengthStudiesTrials
Carcinoma 256, Walker
A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)		01.9910
Hypospermatogenesis
[description not available]		04.0631
Cancer of Lung
[description not available]		0210
Malignant Melanoma
[description not available]		0210
Cancer of Skin
[description not available]		0210
Lung Neoplasms
Tumors or cancer of the LUNG.		0210
Melanoma
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)		0210
Skin Neoplasms
Tumors or cancer of the SKIN.		0210
Weight Gain
Increase in BODY WEIGHT over existing weight.		02.3820
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.		02.6730
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		01.9710