Page last updated: 2024-12-05

siduron

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID16116
CHEMBL ID1902120
CHEBI ID81744
SCHEMBL ID66323
MeSH IDM0053812

Synonyms (45)

Synonym
1982-49-6
tupersan
1-(2-methylcycohexyl)-3-phenylurea
urea, n-(2-methylcyclohexyl)-n'-phenyl-
nsc131951
trey
nsc-131951
1-(2-methylcyclohexyl)-3-phenylurea
du pont herbicide 1,318
h 1318
n-phenyl-n'-(2-methylcyclohexyl)urea
wln: l6tj amvmr& b1
siduron
urea, 1-(2-methylcyclohexyl)-3-phenyl-
NCGC00163937-02
NCGC00163937-01
caswell no. 733a
einecs 217-844-2
nsc 131951
hsdb 1764
du pont 1318
n-(2-methylcyclohexyl)-n'-phenylurea
siduron [ansi:bsi:iso]
dupont 1318
epa pesticide chemical code 035509
AKOS001192124
C18435
513s964ljo ,
unii-513s964ljo
cas-1982-49-6
tox21_301425
NCGC00255363-01
dtxsid7032474 ,
dtxcid5012474
SCHEMBL66323
n-(2-methylcyclohexyl)-n'-phenylurea [hsdb]
siduron [iso]
siduron [mi]
CHEBI:81744 ,
CHEMBL1902120
n-(2-methylcyclohexyl)-n'-phenylurea #
JXVIIQLNUPXOII-UHFFFAOYSA-N
urea,n-(2-methylcyclohexyl)-n'-phenyl-
siduron, pestanal(r), analytical standard
Q27155591
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
ureas
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (17)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency35.57420.007215.758889.3584AID1224835
pregnane X receptorRattus norvegicus (Norway rat)Potency50.11870.025127.9203501.1870AID651751
RAR-related orphan receptor gammaMus musculus (house mouse)Potency9.68850.006038.004119,952.5996AID1159521; AID1159523
AR proteinHomo sapiens (human)Potency0.15480.000221.22318,912.5098AID743036
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency40.28110.001022.650876.6163AID1224838; AID1224839; AID1224893
progesterone receptorHomo sapiens (human)Potency30.63790.000417.946075.1148AID1346795
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency41.99250.003041.611522,387.1992AID1159552; AID1159553; AID1159555
retinoid X nuclear receptor alphaHomo sapiens (human)Potency3.48150.000817.505159.3239AID1159527; AID1159531; AID588544
pregnane X nuclear receptorHomo sapiens (human)Potency24.72770.005428.02631,258.9301AID1346982; AID720659
estrogen nuclear receptor alphaHomo sapiens (human)Potency72.77420.000229.305416,493.5996AID1259244; AID743079
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency44.66840.023723.228263.5986AID588543
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency48.55770.001723.839378.1014AID743083
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.01580.010039.53711,122.0200AID588547
histone deacetylase 9 isoform 3Homo sapiens (human)Potency38.82670.037617.082361.1927AID1259364; AID1259388
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency41.46700.000627.21521,122.0200AID651741; AID720636
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency68.58960.001557.789015,848.9004AID1259244
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency68.58960.001551.739315,848.9004AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
plasma membraneGlutamate receptor 2Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 24.49

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index24.49 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index5.33 (4.65)
Search Engine Demand Index40.41 (26.88)
Search Engine Supply Index4.00 (0.95)

This Compound (24.49)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]