Compounds > sarcodonin g
Page last updated: 2024-11-12

sarcodonin g

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

sarcodonin G: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11162884
CHEMBL ID1802072
MeSH IDM0365679

Synonyms (4)

Synonym
sarcodonin g
CHEMBL1802072
sarcodonins g
(3ar,5ar,10ar)-1-[(2s)-1-hydroxypropan-2-yl]-3a,5a-dimethyl-6-oxo-3,4,5,7,10,10a-hexahydro-2h-cyclohepta[e]indene-8-carbaldehyde
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID606249Neuritogenic activity in rat PC12 cells in serum free medium assessed as potentiation of NGF-induced neurite outgrowth at 25 uM after 24 hrs by light microscopy in presence of 20 ng/ml NGF2011European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
Cyathane diterpenes from Chinese mushroom Sarcodon scabrosus and their neurite outgrowth-promoting activity.
AID652971Increase of NGF-mediated neurite outgrowth in rat PC12 cells after 24 hrs by light microscopy2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
Scabronine M, a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells from the fungus Sarcodon scabrosus.
AID606250Neuritogenic activity in rat PC12 cells in serum free medium assessed as potentiation of NGF-induced neurite outgrowth at 25 uM after 24 hrs by light microscopy in presence of 20 ng/ml NGF relative to NGF2011European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
Cyathane diterpenes from Chinese mushroom Sarcodon scabrosus and their neurite outgrowth-promoting activity.
AID652956Inhibition of NGF-mediated neurite outgrowth in rat PC12 cells after 24 hrs by light microscopy2012Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
Scabronine M, a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells from the fungus Sarcodon scabrosus.
AID606251Neuritogenic activity in rat PC12 cells in serum free medium assessed as neurite outgrowth at 25 uM after 24 hrs by light microscopy2011European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
Cyathane diterpenes from Chinese mushroom Sarcodon scabrosus and their neurite outgrowth-promoting activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.82 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.77 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ergosterol
[no description available]		2.07103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
ergosta-7,22-dien-3-ol, (3beta,5alpha,6alpha,22e)-isomer
5alpha-ergosta-7,22-dien-3beta-ol : A 3beta-sterol consisting of an ergostane skeleton with double bonds at 7- and 22-positions.		2.07103beta-sterolanti-HSV-1 agent;
antifungal agent;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
metabolite
ergosterol-5,8-peroxide
ergosterol-5,8-peroxide: also inhibits sulfatase; isolated from fungus Cercospora kikuchii; structure given in first source. ergosterol peroxide : An ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities.		2.07103beta-sterol;
ergostanoid;
organic peroxide;
phytosterols		antimycobacterial drug;
antineoplastic agent;
metabolite;
trypanocidal drug
sarcodonin m
sarcodonin M: isolated from Sarcodon scabrosus; structure in first source		2.0610
cerevisterol
cerevisterol: in mushroom family; Russian. cerevisterol : An ergostanoid that is (22E)-ergosta-7,22-diene substituted by hydroxy groups at positions 3, 5 and 6 (the 3beta,5alpha,6beta stereoisomer). It has been isolated from the fungus, Xylaria species.		2.07103beta-hydroxy steroid;
5alpha-hydroxy steroid;
6beta-hydroxy steroid;
ergostanoid		Aspergillus metabolite
tuberoside
tuberoside: a steroidal saponin from the seeds of Allium tuberosum; structure in first source		2.0710steroid saponin
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		02.0510
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.0510