s-ribosyl-l-homocysteine profile

S-ribosyl-L-homocysteine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

S-(5-deoxy-beta-D-ribos-5-yl)-L-homocysteine : An S-(5-deoxy-D-ribos-5-yl)-L-homocysteine in which the anomeric centre has beta-configuration. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	440041
CHEBI ID	90364
MeSH ID	M0468457

Synonym
RHC ,
(2s)-2-amino-4-[[(2s,3s,4r,5r)-3,4,5-trihydroxyoxolan-2-yl]methylsulfanyl]butanoic acid
s-ribosyl-l-homocysteine
5-(3-amino-4,4-dihyroxy-butylsulfanylmethyl)-tetrahydro-furan-2,3,4-triol
DB02321
CPD-564 ,
CHEBI:90364
(2s)-2-amino-4-({[(2s,3s,4r,5r)-3,4,5-trihydroxytetrahydro-2-furanyl]methyl}sulfanyl)butanoic acid
s-(5-deoxy-beta-d-ribos-5-yl)-l-homocysteine
(2s)-2-amino-4-({[(2s,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred
Q19830763
PD060162
DTXSID001344124

Role	Description
Escherichia coli metabolite	Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
S-(5-deoxy-D-ribos-5-yl)-L-homocysteine
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (5.88)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (58.82)	29.6817
2010's	5 (29.41)	24.3611
2020's	1 (5.88)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (11.76%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	15 (88.24%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
carbamates [no description available]	2.03	1	amino-acid anion
safrole Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).. safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.	1.93	1	benzodioxoles	flavouring agent; insecticide; metabolite; plant metabolite
trifluoroacetic acid Trifluoroacetic Acid: A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.. trifluoroacetic acid : A monocarboxylic acid that is the trifluoro derivative of acetic acid.	2.11	1	fluoroalkanoic acid	human xenobiotic metabolite; NMR chemical shift reference compound; reagent
pentane Pentanes: Five-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.. pentane : A straight chain alkane consisting of 5 carbon atoms.	3.12	1	alkane; volatile organic compound	non-polar solvent; refrigerant
sulfoxide sulfoxide: synergistic insecticide for use with pyrethrum, allethrin, rotenone, ryania, etc.; RN given refers to parent cpd; structure. sulfoxide : An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H).	6.93	1	benzodioxoles
homocystine [no description available]	2.11	1	amino acid zwitterion; homocystines	human metabolite
homoserine homoserine : An alpha-amino acid that is glycine substituted at the alpha-position by a 2-hydroxyethyl group.. L-homoserine : The L-enantiomer of homoserine.	2.74	3	amino acid zwitterion; homoserine	algal metabolite; Escherichia coli metabolite; human metabolite; Saccharomyces cerevisiae metabolite
homocysteine Homocysteine: A thiol-containing amino acid formed by a demethylation of METHIONINE.. homocysteine : A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.. L-homocysteine : A homocysteine that has L configuration.	5.84	17	amino acid zwitterion; homocysteine; serine family amino acid	fundamental metabolite; mouse metabolite
4,5-dihydroxy-2,3-pentanedione 4,5-dihydroxy-2,3-pentanedione: structure in first source	3.12	1
sulfur Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.	2.47	2	chalcogen; nonmetal atom	macronutrient
cysteine Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.	6.93	1	cysteinium	fundamental metabolite
ribose ribopyranose : The pyranose form of ribose.	2.46	2	D-ribose; ribopyranose

Condition	Relationship Strength	Studies
Avian Diseases [description not available]	2.07	1
E coli Infections [description not available]	2.07	1
Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI.	2.07	1

s-ribosyl-l-homocysteine

Description

Cross-References

Synonyms (13)

Roles (1)

Drug Classes (1)

Research

Studies (17)

Market Indicators

Research Demand Index: 11.30

Study Types