radicamine b profile

radicamine B: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	15953621
CHEMBL ID	466791
SCHEMBL ID	13848027
MeSH ID	M0419017

Synonyms (8)

Synonym
(2r,3r,4r,5r)-2-(hydroxymethyl)-5-(4-hydroxyphenyl)pyrrolidine-3,4-diol
7E79EEAE-B5A3-481B-A039-B6DA9C270415
CHEMBL466791
radicamine b
SCHEMBL13848027
431981-75-8
XR175854
3,4-pyrrolidinediol,2-(hydroxymethyl)-5-(4-hydroxyphenyl)-,(2s,3s,4s,5s)-(9ci)

Bioassays (4)

Assay ID	Title	Year	Journal	Article
AID412140	Inhibition of Helix pomatia beta-mannosidase	2008	Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24	Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library.
AID412139	Inhibition of yeast alpha-glucosidase	2008	Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24	Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library.
AID412141	Inhibition of almond beta-glucosidase	2008	Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24	Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library.
AID412138	Inhibition of Bacillus stearothermophilus alpha-glucosidase	2008	Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24	Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.43 (24.57)
Research Supply Index	1.95 (2.92)
Research Growth Index	4.37 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.43)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
serine Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.. serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.	2.04	1	L-alpha-amino acid; proteinogenic amino acid; serine family amino acid; serine zwitterion; serine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
mannitol [no description available]	7.1	1	mannitol	allergen; antiglaucoma drug; compatible osmolytes; Escherichia coli metabolite; food anticaking agent; food bulking agent; food humectant; food stabiliser; food thickening agent; hapten; metabolite; osmotic diuretic; sweetening agent
nectrisine nectrisine: produced by the fungus, Nectria lucida F-4490; structure given in first source	7.04	1
xylose xylopyranose: structure in first source	2.03	1	D-xylose
piperidines Piperidines: A family of hexahydropyridines.	2.13	1

radicamine b

Description