Page last updated: 2024-12-11

neorustmicin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

neorustmicin A: active against wheat stem rust fungus; isolated from Micromonospora chalcea 1302-AV2; MF C21-H32-O5; structure given in first source; has also been isolated from Streptomyces galbus [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6438862
CHEMBL ID284267
MeSH IDM0137829

Synonyms (5)

Synonym
100157-26-4
neorustmicin a
CHEMBL284267
(3r,5s,7e,9s,12e,14s)-14-ethyl-5-hydroxy-5-(hydroxymethyl)-3,7,9,13-tetramethyl-11-methylidene-1-oxacyclotetradeca-7,12-diene-2,4-dione
erythronolide a, 6,7,10,11,12,20-hexadehydro-9-deoxo-3,5,6,11,12-pentadeoxy-4,17-dihydroxy-3-oxo-
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID39699In vitro antifungal activity against Aspergillus fumigatus TIMM1776; activity expressed as minimum inhibitory concentration2004Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
Novel galbonolide derivatives as IPC synthase inhibitors: design, synthesis and in vitro antifungal activities.
AID45478In vitro antifungal activity against Candida albicans ATCC 90028; activity expressed as minimum inhibitory concentration2004Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
Novel galbonolide derivatives as IPC synthase inhibitors: design, synthesis and in vitro antifungal activities.
AID202873In vitro antifungal activity against Saccharomyces cerevisiae Y9; activity expressed as minimum inhibitory concentration2004Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
Novel galbonolide derivatives as IPC synthase inhibitors: design, synthesis and in vitro antifungal activities.
AID55035In vitro antifungal activity against Cryptococcus neoformans ATCC 9011; activity expressed as minimum inhibitory concentration2004Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
Novel galbonolide derivatives as IPC synthase inhibitors: design, synthesis and in vitro antifungal activities.
AID54870In vitro antifungal activity against Cryptococcus neoformans ATCC 90112004Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
Novel galbonolide derivatives as IPC synthase inhibitors: design, synthesis and in vitro antifungal activities.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.54

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.54 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.54)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]