| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
inositol
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.. inositol : Any cyclohexane-1,2,3,4,5,6-hexol.. 1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.. muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration. | 6.99 | 1 | 0 | cyclitol;
hexol | |
australifungin
australifungin: contains a combination of alpha-diketone and beta-ketoaldehyde groups; from Sporormiella australis; inhibits sphinganine N-acyltransferase (ceramide synthetase); structure given in first source. australifungin : A carbobicyclic compound that is 4a,5,6,7,8,8a-hexahydronaphthalen-1(4H)-one substituted by hydroxy groups at positions 2, 5 and 8, a (2Z)-3-hydroxyprop-2-enoyl group at position 4, methyl groups at positions 4 and 7 and a 2R-octan-2-yl group at position 3 (the 4S,4aR,5S,7R,8R,8aS stereoisomer). It is isolated from the fermentation extracts of Sporormiella australis and exhibits antifungal activity by interfering with the fungal lipid metabolism. | 7 | 1 | 0 | carbobicyclic compound;
enol;
enone;
secondary alcohol | antifungal agent;
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor;
HIV-1 integrase inhibitor;
metabolite |
neorustmicin a
neorustmicin A: active against wheat stem rust fungus; isolated from Micromonospora chalcea 1302-AV2; MF C21-H32-O5; structure given in first source; has also been isolated from Streptomyces galbus | 2.9 | 4 | 0 | | |
khafrefungin
khafrefungin: inhibits inositol phosphoceramide synthase in fungi; structure in first source | 8.51 | 2 | 0 | | |
r-106
[no description available] | 3.52 | 2 | 0 | | |
glycolipids
[no description available] | 3.51 | 2 | 0 | | |