Page last updated: 2024-12-11
ms 8209
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
MS 8209: an amphotericin B derivative with antifungal and antiviral properties; inhibits HIV-1 replication; prevents membrane expression of HIV-1 large envelope glycoprotein gp120; tested against scrapie [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 6436189 |
MeSH ID | M0201506 |
Synonyms (6)
Synonym |
---|
ms-8209 , |
ms 8209 |
ms8209 |
1-deoxy-1-amino-4,6-o-benzylidene-d-fructosyl amphotericin b, n-methyl glucamine salt |
136458-97-4 |
1-deoxy-1-amino-4,6-o-benzylidene-fructosyl-amphotericin b |
Research Excerpts
Dosage Studied
Excerpt | Relevance | Reference |
---|---|---|
", the dosage inducing less than 15% mortality due to toxicity; the efficacies of MS-8209 and D-AmB at their respective maximum tolerated dosages were compared." | ( Activity of MS-8209, a nonester amphotericin B derivative, in treatment of experimental systemic mycoses. Carbon, C; Joly, V; Saint-Julien, L; Seman, M; Yeni, P, 1992) | 0.28 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (17)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (58.82) | 18.2507 |
2000's | 7 (41.18) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 25.79
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (25.79) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (5.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 19 (95.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |