knt-127 and 7-benzylidenenaltrexone

knt-127 has been researched along with 7-benzylidenenaltrexone* in 1 studies

Other Studies

1 other study(ies) available for knt-127 and 7-benzylidenenaltrexone

ArticleYear
Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives.
    Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16

    The 7-benzylidenenaltrexone (BNTX) derivatives 2a-v, 3a-c, 13a-c, and 14a were synthesized from naltrexone (1) and evaluated for their antitrichomonal activity. The structure-activity-relationship studies found that 4-iodo-BNTX (2g) showed the highest activity (IC

    Topics: Animals; Antitrichomonal Agents; Benzylidene Compounds; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Molecular Structure; Naltrexone; Receptors, Opioid, delta; Structure-Activity Relationship; Trichomonas vaginalis

2017