Compounds > isoputreanine
Page last updated: 2024-12-08

isoputreanine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

isoputreanine: metabolite of spermidine; RN given refers to parent cpd or spermine in human urine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID171763
CHEBI ID165866
SCHEMBL ID11439892
MeSH IDM0107909

Synonyms (21)

Synonym
isoputreanine
66165-33-1
4-(3-aminopropylamino)butanoic acid
CHEBI:165866
butanoic acid, 4-((3-aminopropyl)amino)-
AKOS011558576
SCHEMBL11439892
DTXSID30216354
4-[(3-aminopropyl)amino]butanoic acid
n-(3-aminopropyl)-4-aminobutanoic acid
4-((3-aminopropyl)amino)-butanoic acid
n-(3-aminopropyl)-4-aminobutyrate
n-(3-aminopropyl)-4-aminobutanoate
4-((3-aminopropyl)amino)-butanoate
n-(4-carboxybutyl)-1,3-propanediamine
n-(4-carboxybutyl)-1,3-diaminopropane
n-(3-aminopropyl)-4-aminobutyric acid
4-((3-aminopropyl)amino)butanoic acid
CS-0346048
EN300-191665
STARBLD0041603
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
organooxygen compoundAn organochalcogen compound containing at least one carbon-oxygen bond.
organonitrogen compoundAny heteroorganic entity containing at least one carbon-nitrogen bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.60

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.60 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.39 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.60)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
cadaverine
[no description available]		1.9610alkane-alpha,omega-diamineDaphnia magna metabolite;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite
trimethylenediamine
trimethylenediamine: RN given refers to parent cpd; structure. trimethylenediamine : An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.		1.9610alkane-alpha,omega-diaminehuman metabolite;
mouse metabolite;
reagent
n(1)-acetylspermidine
N(1)-acetylspermidine : An acetylspermidine having the acetyl group at the N1-position.		2.3720acetylspermidineEscherichia coli metabolite;
metabolite
n'-acetylspermine
N(1)-acetylspermine : An acetylspermine carrying an acetyl group at position N(1).		1.9710acetamides;
acetylspermine		human metabolite
spermidine
[no description available]		8.0650polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
spermine
[no description available]		7.6630polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
n',n''-diacetylspermine
N',N''-diacetylspermine: intermediate in polyamine catabolism		1.9710acetamides
putreanine
[no description available]		2.3620carboxylic acid anion;
N-substituted putrescine;
organonitrogen compound;
organooxygen compound
ConditionIndicatedRelationship StrengthStudiesTrials
Germinoblastoma
[description not available]		02.3620
Malignant Melanoma
[description not available]		01.9610
Lymphoma
A general term for various neoplastic diseases of the lymphoid tissue.		02.3620
Melanoma
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)		01.9610
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		01.9610
Cerebro-Hepato-Renal Syndrome
[description not available]		01.9710
Zellweger Syndrome
An autosomal recessive disorder due to defects in PEROXISOME biogenesis which involves more than 13 genes encoding peroxin proteins of the peroxisomal membrane and matrix. Zellweger syndrome is typically seen in the neonatal period with features such as dysmorphic skull; MUSCLE HYPOTONIA; SENSORINEURAL HEARING LOSS; visual compromise; SEIZURES; progressive degeneration of the KIDNEYS and the LIVER. Zellweger-like syndrome refers to phenotypes resembling the neonatal Zellweger syndrome but seen in children or adults with apparently intact peroxisome biogenesis.		01.9710