Compounds > iopronic acid
Page last updated: 2024-11-06

iopronic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Iopronic acid is a synthetically derived compound that has shown potential as an anti-inflammatory agent. Its structure is similar to that of propionic acid, a natural compound found in the body, and it is believed to work by inhibiting the production of certain inflammatory mediators. Research on iopronic acid is ongoing to explore its therapeutic potential in various inflammatory conditions.'

iopronic acid: RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID37822
CHEMBL ID2105012
CHEBI ID135869
SCHEMBL ID668046
SCHEMBL ID20394773
MeSH IDM0049483

Synonyms (15)

Synonym
iopronic acid
D04585
bilimiron (tn)
iopronic acid (usan/inn)
37723-78-7
CHEBI:135869
2-[2-(3-acetamido-2,4,6-triiodophenoxy)ethoxymethyl]butanoic acid
so-21983
CHEMBL2105012
so 21983
SCHEMBL668046
SCHEMBL20394773
3-[2-(3-acetylamino-2,4,6-triiodophenoxy)ethoxy]-2-ethylpropionic acid
DTXSID30865881
2-{[2-(3-acetamido-2,4,6-triiodophenoxy)ethoxy]methyl}butanoic acid

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Drug-related abnormalities in blood and urine tests occurred about equally in both groups and one patient in each group exhibited a clinically adverse reaction (diarrhea)."( Clinical comparison of two contrast agents for oral cholecystography: radiologic efficacy and drug safety of iopanoic acid and iopronic acid.
Burrell, M; Hedlund, L; Putman, CE, )		0.34
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
aromatic amideAn amide in which the amide linkage is bonded directly to an aromatic system.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.74

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.74 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.74)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials3 (27.27%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (63.64%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbon monoxide
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed). carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.		1.9510carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
iopanoic acid
Iopanoic Acid: Radiopaque medium used as diagnostic aid.		9.8521monocarboxylic acid
ipodate
Ipodate: Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)		3.0610
iophenoxic acid
iophenoxic acid: structure		3.0610benzenes;
monocarboxylic acid
buniodyl
buniodyl: RN given refers to parent cpd		3.0610cinnamic acids
ConditionIndicatedRelationship StrengthStudiesTrials
Chronic Illness
[description not available]		01.9510
Liver Dysfunction
[description not available]		01.9510
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).		01.9510
Liver Diseases
Pathological processes of the LIVER.		01.9510