| Assay ID | Title | Year | Journal | Article |
|---|
| AID684275 | Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells at 5 to 20 uM after 3 to 24 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684084 | Downregulation of MMP9 expression in human MDA-MB-231 cells at 0.1 to 0.9 uM after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684089 | Upregulation of TIMP2 expression in human MDA-MB-231 cells at 1.1 to 3.6 uM after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684285 | Antiinvasive activity against human MDA-MB-231 cells xenografted in athymic nude BALB/c mouse assessed as decrease in lung metastasis at 5 and 20 mg/kg, ip administered 3 times per week starting 1 week prior to xenografting measured after 5 weeks by hemat | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684081 | Inhibition of MMP2 in human MDA-MB-231 cells at 20 uM up to 12 hrs by gelatin-zymogrphy | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684077 | Antimetastatic activity against human MDA-MB-231 cells assessed as inhibition of wound closure activity up to 20 uM at 12 hrs by scratch motility assay | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684075 | Cytotoxicity against human MDA-MB-231 cells at 25 to 100 uM after 24 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684086 | Upregulation of TIMP1 expression in human MDA-MB-231 cells at 0.2 to 0.8 uM after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684083 | Downregulation of MMP2 expression in human MDA-MB-231 cells at 5 to 20 uM after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684079 | Inhibition of FAK phosphorylation in human MDA-MB-231 cells after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684286 | Antiinvasive activity against human SKHEP1 cells | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684278 | Inhibition of ERK 1/2 phosphorylation in human MDA-MB-231 cells at 5 to 20 uM after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684078 | Antiinvasive activity against human MDA-MB-231 cells assessed as F-actin reorganization at 20 uM incubated 24 hrs post-serum starvation measured after 12 hrs by TRITC-conjugated phalloidin staining method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684283 | Antiinvasive activity against human MDA-MB-231 cells xenografted in athymic nude BALB/c mouse assessed as decrease in lung size at 5 and 20 mg/kg, ip administered 3 times per week starting 1 week prior to xenografting measured after 5 weeks relative to co | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684082 | Inhibition of MMP9 in human MDA-MB-231 cells at 20 uM up to 12 hrs by gelatin-zymogrphy | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684080 | Antiinvasive activity against human MDA-MB-231 cells pretreated for 12 hrs followed by compound-wash out measured after 12 hrs by Boyden chamber assay | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684284 | Antiinvasive activity against human MDA-MB-231 cells xenografted in athymic nude BALB/c mouse assessed as decrease in lung weight at 5 and 20 mg/kg, ip administered 3 times per week starting 1 week prior to xenografting measured after 5 weeks relative to | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684076 | Antimetastatic activity against human MDA-MB-231 cells assessed as inhibition of anchorage-independent colony formation after 21 days by inverted microscopy | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| AID684277 | Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells after 12 hrs by Western blot analysis | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |