Compounds > chaulmoogric acid
Page last updated: 2024-11-06

chaulmoogric acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

chaulmoogric acid: component of CHAULMOOGRA OIL; RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

(R)-chaulmoogric acid : The (R)-enantiomer of chaulmoogric acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

chaulmoogric acid : A monounsaturated long-chain fatty acid composed of tridecanoic acid having a 2-cyclopentenyl substituent at the 13-position. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID12302887
CHEBI ID61389
SCHEMBL ID560850
MeSH IDM0067600

Synonyms (19)

Synonym
2-cyclopentene-1-tridecanoic acid
chaulmoogric acid
(r)-13-(cyclopent-2-en-1-yl)tridecanoic acid
(r)-2-cyclopentene-1-tridecanoic acid
(r)-chaulmoogric acid
13-[(r)-cyclopent-2-enyl]-tridecansauere
13-[(1r)-cyclopent-2-en-1-yl]tridecanoic acid
(+)-chaulmoograsauere
13-(r)-cyclopent-2-enyl-tridecansaeure
acido (r)-chaulmogrico
CHEBI:61389
13-(r)-cyclopent-2-enyl-tridecanoic acid
acide (r)-chaulmoogrique
13-[(r)-cyclopent-2-enyl]-tridecanoic acid
LMFA01140017
13-(2-cyclopenten-1-yl)tridecanoic acid
13r-(2-cyclopentenyl)-tridecanoic acid
13-(cyclopent-2-enyl)-n-tridecanoic acid
SCHEMBL560850
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
chaulmoogric acidA monounsaturated long-chain fatty acid composed of tridecanoic acid having a 2-cyclopentenyl substituent at the 13-position.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
4-nitrophenylphosphate
nitrophenylphosphate: RN given refers to mono(4-nitrophenyl) ester of phosphoric acid. 4-nitrophenyl phosphate : An aryl phosphate resulting from the mono-esterification of phosphoric acid with 4-nitrophenol.		2.0510aryl phosphatemouse metabolite
clofazimine
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619). clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.		1.9510monochlorobenzenes;
phenazines		dye;
leprostatic drug;
non-steroidal anti-inflammatory drug
dapsone
[no description available]		1.9810substituted aniline;
sulfone		anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug
cyclopentane
Cyclopentanes: A group of alicyclic hydrocarbons with the general formula R-C5H9.. cyclopentanes : Cyclopentane and its derivatives formed by substitution.		2.6530cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
hydnocarpic acid
hydnocarpic acid: cyclopentenyl fatty acid; component of chaulmoogra oil. hydnocarpic acid : A cyclopentenyl fatty acid consisting of undecanoic acid having a cyclopent-2-enyl group at the 11-position.		1.9810cyclopentenyl fatty acid;
long-chain fatty acid;
monounsaturated fatty acid
arachidonic acid
icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.. arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid.		2.0510icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
nitrophenols
Nitrophenols: PHENOLS carrying nitro group substituents.		2.0510
ConditionIndicatedRelationship StrengthStudiesTrials
Hansen Disease
[description not available]		01.9810
Leprosy
A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.		01.9810
Infections, Mycobacterium
[description not available]		01.9510
Mycobacterium Infections
Infections with bacteria of the genus MYCOBACTERIUM.		01.9510