Compounds > 2,2',3,3',4,6'-hexachlorobiphenyl
Page last updated: 2024-12-06
2,2',3,3',4,6'-hexachlorobiphenyl
Description
2,2',3,3',4,6'-hexachlorobiphenyl, also known as PCB 153, is a highly chlorinated polychlorinated biphenyl (PCB) congener. It is a persistent organic pollutant (POP) with a long half-life in the environment. PCBs were widely used in industrial applications, such as electrical transformers and capacitors, due to their electrical insulating properties, thermal stability, and resistance to chemical degradation. However, their persistence and toxicity led to their ban in many countries. PCB 153 has been shown to be toxic to various organisms, including fish, birds, and mammals. It can accumulate in the food chain and has been associated with adverse health effects in humans, including reproductive problems, cancer, and neurodevelopmental disorders. Research on PCB 153 focuses on its environmental fate, toxicity, and potential health risks. Understanding its properties and behavior is crucial for developing strategies to mitigate its environmental and health impacts.'
2,2',3,3',4,6'-hexachlorobiphenyl: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 38017 |
| SCHEMBL ID | 4453307 |
| MeSH ID | M0249855 |
Synonyms (20)
| Synonym |
|---|
| 1,1'-biphenyl, 2,2',3,3',4,6'-hexachloro- |
| 2,2',3,3',4,6'-hexachloro-1,1'-biphenyl |
| pcb 132 |
| gpcb 132 |
| 2,2',3,3',4,6'-hexachlorobiphenyl |
| 38380-05-1 |
| 1,2,3-trichloro-4-(2,3,6-trichlorophenyl)benzene |
| 814t8d9w95 , |
| unii-814t8d9w95 |
| 2,2,3,3,4,6-hexachloro-1,1-biphenyl |
| SCHEMBL4453307 |
| OKBJVIVEFXPEOU-UHFFFAOYSA-N |
| 2,2',3,3',4,6'-hexachloro-1,1'-biphenyl # |
| DTXSID9074141 , |
| pcb no. 132 10 microg/ml in isooctane |
| pcb no. 132 |
| 3-(carboxymethyl)benzothiazoliumbromide |
| Q27269208 |
| CS-0451960 |
| dtxcid5039486 |
Research Excerpts
Dosage Studied
| Excerpt | Relevance | Reference |
|---|
| " CB 132 (2,2',3,3',4,6'-hexachlorophenyl) and CB 149 (2,2'3,4',5',6-hexachlorophenyl) were investigated in weanling female rats dosed intraperitoneally on days 21 and 22 and killed on day 24 of age." | ( Hepatic enzyme induction and acute endocrine effects of 2,2',3,3',4,6'-hexachlorobiphenyl and 2,2',3,4',5',6-hexachlorobiphenyl in prepubertal female rats.
Guo, YL; Hsu, PC; Li, MH, 2001) | 0.56 |
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.96
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.96 (24.57) | | Research Supply Index | 2.08 (2.92) | | Research Growth Index | 5.04 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |