Compounds > cb 149
Page last updated: 2024-12-06

cb 149

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,2',3,4',5',6-hexachlorobiphenyl: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID38016
SCHEMBL ID4450440
MeSH IDM0332565

Synonyms (25)

Synonym
2,2',3,4',5',6-hexachloro-1,1'-biphenyl
1,1'-biphenyl, 2,2',3,4',5',6-hexachloro-
pcb-149
pcb 149
2,2',3',4,5,6'-hexachlorobiphenyl
cb149
pcb149
cb 149
2,2',3,4',5',6-hexachlorobiphenyl
pcb no 149
1,2,4-trichloro-3-(2,4,5-trichlorophenyl)benzene
5jns37uvgi ,
38380-04-0
unii-5jns37uvgi
SCHEMBL4450440
1,1'-biphenyl, 2,2',3',4,5,6'-hexachloro
LKHLFUVHHXCNJH-UHFFFAOYSA-N
2,2'3,4',5',6-hexachloro-1,1'-biphenyl
2,2',3,4',5',6-hexachloro-1,1'-biphenyl #
DTXSID1073498 ,
pcb no 149, analytical standard
pcb no. 149
pcb no. 149 10 microg/ml in isooctane
Q27262462
dtxcid0039485

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" CB 132 (2,2',3,3',4,6'-hexachlorophenyl) and CB 149 (2,2'3,4',5',6-hexachlorophenyl) were investigated in weanling female rats dosed intraperitoneally on days 21 and 22 and killed on day 24 of age."( Hepatic enzyme induction and acute endocrine effects of 2,2',3,3',4,6'-hexachlorobiphenyl and 2,2',3,4',5',6-hexachlorobiphenyl in prepubertal female rats.
Guo, YL; Hsu, PC; Li, MH, 2001)		0.57
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.38

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.38 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.95 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.38)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
thyroxine
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.. thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.		2102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
triiodothyronine
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.. 3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.		2.01102-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
2,4,5,2',5'-pentachlorobiphenyl
[no description available]		210
2,2',3,3',4,6'-hexachlorobiphenyl
2,2',3,3',4,6'-hexachlorobiphenyl: structure given in first source		2.4120
ConditionIndicatedRelationship StrengthStudiesTrials