1-chloro-2-hydroxy-3-butene is a chemical compound with the formula CH2=CHCH(OH)CH2Cl. It's a **reactive intermediate** that is not typically isolated or used directly in research. It's **important as a potential precursor** to other compounds and can be involved in various **chemical reactions** and **synthetic processes**.
**Here's why it's important in research:**
* **Precursor to other valuable compounds:** It can be used as a building block for synthesizing various organic compounds, including pharmaceutical agents, agrochemicals, and materials.
* **Study of reaction mechanisms:** Researchers may study the reactions involving 1-chloro-2-hydroxy-3-butene to understand the mechanisms and kinetics of chemical transformations. This can lead to developing new synthetic methods or catalysts.
* **Exploration of chemical reactivity:** Due to its reactive nature, it can be used to investigate the reactivity of different functional groups and explore the potential of new chemical reactions.
**However, it's important to note that 1-chloro-2-hydroxy-3-butene is a highly reactive compound.** It's often generated in situ (within a reaction mixture) and not isolated. This is because it's prone to decomposition and may be difficult to handle.
**To summarize, while not a commonly used compound itself, 1-chloro-2-hydroxy-3-butene plays a significant role in research as a potential precursor, a tool for studying reaction mechanisms, and a substrate for exploring chemical reactivity.**
ID Source | ID |
---|---|
PubMed CID | 12642 |
SCHEMBL ID | 8781922 |
MeSH ID | M0207450 |
Synonym |
---|
671-56-7 |
3-buten-2-ol, 1-chloro- |
1-chloro-2-hydroxy-3-butene |
1-chb |
1-chlorobut-3-en-2-ol |
AKOS006382359 |
SCHEMBL8781922 |
1-chloro-but-3-en-2-ol |
DTXSID60870746 |
Excerpt | Reference | Relevance |
---|---|---|
" The Ames test results showed that CHB induced point mutation but not frameshift mutation, whereas the toxic effects of CBO made it difficult to reliably assess the mutagenic potential of CBO in the two strains." | ( Cytotoxicity, genotoxicity, and mutagenicity of 1-chloro-2-hydroxy-3-butene and 1-chloro-3-buten-2-one, two alternative metabolites of 1,3-butadiene. An, J; Elfarra, AA; Liu, XJ; Yu, YX; Zeng, FM; Zhang, XY, 2013) | 0.65 |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.53) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |