Page last updated: 2024-11-11

penicillin f

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

penicillin F: RN given refers to (2S-(2alpha,5alpha,6beta))-isomer; RN for cpd without isomeric designation not avail 3/91 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6438232
CHEBI ID81063
MeSH IDM0183938

Synonyms (25)

Synonym
flavicidin
penicillin f
penicillin i
3,3-dimethyl-6-(3-hexenamido)-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
delta(sup 2)-pentenylpenicillin
2-pentenylpenicillin
delta-beta,gamma-pentenylpenicillin
4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-(3-hexenamido)-7-oxo-
C17402
118-53-6
(2s,5r,6r)-6-[[(e)-hex-3-enoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
88ey1ap5ur ,
unii-88ey1ap5ur
CHEBI:81063
penicillin f [mi]
(2s,5r,6r)-6-((3z)-hex-3-enamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
benzathine benzylpenicillin impurity h [ep impurity]
4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((1-oxo-3-hexen-1-yl)amino)-, (2s,5r,6r)-
(2s,5r,6r)-6-((3z)-hex-3-enoylamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
benzylpenicillin sodium impurity g [ep impurity]
isopenicillin f
benzylpenicillin (benzathine) tetrahydrate impurity h [ep impurity]
benzylpenicillin potassium impurity g [ep impurity]
DTXSID90151994
Q27155019

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In both man and rabbit, penicillin X provided higher and more sustained blood levels than did penicillins F or G similarly administered in equal dosage (0."( THE VARYING BLOOD LEVELS AFFORDED BY PENICILLINS F, G, K, AND X IN RABBITS AND MAN.
Eagle, H, 1947
)
0.23
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
penicillinAny member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-199015 (93.75)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 28.62

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index28.62 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index4.27 (4.65)
Search Engine Demand Index34.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (28.62)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]