Compounds > penicillin k
Page last updated: 2024-11-12

penicillin k

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

penicillin K: biosynthesized from glutathione S-derivatives; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID12314049
CHEBI ID81064
SCHEMBL ID649104
MeSH IDM0179395

Synonyms (15)

Synonym
octanoylpenicillin
penicillin k
3,3-dimethyl-6-octanamido-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
penicillin iv
4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-octanamido-7-oxo-
heptylpenicillin
penicillin a
525-97-3
C17403
3,3-dimethyl-6-(octanoylamino)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
SCHEMBL649104
CHEBI:81064
DTXSID80200506
Q27155021
(2s,5r,6r)-3,3-dimethyl-6-(octanoylamino)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In both man and rabbit, penicillin X provided higher and more sustained blood levels than did penicillins F or G similarly administered in equal dosage (0."( THE VARYING BLOOD LEVELS AFFORDED BY PENICILLINS F, G, K, AND X IN RABBITS AND MAN.
Eagle, H, 1947)		0.23
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
penicillinAny member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-199019 (86.36)18.7374
1990's1 (4.55)18.2507
2000's1 (4.55)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 59.93

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index59.93 (24.57)
Research Supply Index3.22 (2.92)
Research Growth Index4.33 (4.65)
Search Engine Demand Index95.68 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (59.93)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.35%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (95.65%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
penicillin g
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.. benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.		4.07160penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope
penicillin v
Penicillin V: A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.. phenoxymethylpenicillin : A penicillin compound having a 6beta-(phenoxyacetyl)amino side-chain.		2.6530penicillin allergen;
penicillin
penicillanic acid
Penicillanic Acid: A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed). penicillanic acid : A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2S,5R)-configuration.		1.9710penicillanic acids
aminopenicillanic acid
aminopenicillanic acid: RN given refers to parent cpd; structure. 6-aminopenicillanic acid : A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics.		1.9710amino acid zwitterion;
penicillanic acids		allergen
penicillin x
penicillin X: RN given refers to (2S-(2alpha,5alpha,6beta))-isomer		3.4380penicillin
penicillin f
penicillin F: RN given refers to (2S-(2alpha,5alpha,6beta))-isomer; RN for cpd without isomeric designation not avail 3/91		3.5390penicillin
ConditionIndicatedRelationship StrengthStudiesTrials
Great Pox
[description not available]		01.9210
Syphilis
A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.		01.9210
Infection
[description not available]		01.9210
Infections, Pneumococcal
[description not available]		01.9210
Group A Strep Infection
[description not available]		01.9210
Infections
Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.		01.9210
Pneumococcal Infections
Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.		01.9210
Streptococcal Infections
Infections with bacteria of the genus STREPTOCOCCUS.		01.9210
Neisseria gonorrhoeae Infection
[description not available]		01.9210
Gonorrhea
Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.		01.9210
Enteric Fever
[description not available]		01.9210
Typhoid Fever
An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.		01.9210