| Assay ID | Title | Year | Journal | Article |
|---|
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID350248 | Cytotoxicity against human P-glycoprotein-expressing KBV1 cells after 72 hrs by MTT assay | 2009 | Journal of medicinal chemistry, May-28, Volume: 52, Issue:10
| Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells. |
| AID458587 | Cytotoxicity against human 184B5 cells after 48 hrs by SRB assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach. |
| AID72520 | Inhibitory activity against Falcipain-2 | 2003 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 13, Issue:20
| Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain. |
| AID458586 | Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach. |
| AID350249 | Cytotoxicity against human P-gp-negative KB-3-1 cells after 72 hrs by MTT assay | 2009 | Journal of medicinal chemistry, May-28, Volume: 52, Issue:10
| Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells. |
| AID309307 | Cytotoxicity against human CEM cells | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis, anticancer, and cytotoxic activities of some mononuclear Ru(II) compounds. |
| AID309306 | Cytotoxicity against human Molt 4/C8 cells | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis, anticancer, and cytotoxic activities of some mononuclear Ru(II) compounds. |
| AID213673 | Inhibitory activity against the Trypanosoma cruzi cysteine protease cruzain | 2003 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 13, Issue:20
| Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain. |
| AID244634 | Ratio of Effective concentration to inhibit cowpox virus plaque formation to that of half maximal cytotoxic concentration in human foreskin fibroblast (HFF) cells | 2005 | Journal of medicinal chemistry, Apr-21, Volume: 48, Issue:8
| Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. |
| AID246355 | Effective concentration required to inhibit cowpox virus plaque formation in human foreskin fibroblast (HFF) cells | 2005 | Journal of medicinal chemistry, Apr-21, Volume: 48, Issue:8
| Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. |
| AID309308 | Cytotoxicity against mouse L1210 cells | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis, anticancer, and cytotoxic activities of some mononuclear Ru(II) compounds. |
| AID628718 | Cytotoxicity against vinblastine-selected human KBV1 cells after 72 hrs by MTT assay | 2011 | Journal of medicinal chemistry, Aug-25, Volume: 54, Issue:16
| Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein. |
| AID628717 | Cytotoxicity against human KB-3-1 cells after 72 hrs by MTT assay | 2011 | Journal of medicinal chemistry, Aug-25, Volume: 54, Issue:16
| Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein. |
| AID200223 | Inhibitory activity against Trypanosoma brucei rhodesiense cysteine protease rhodesain | 2003 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 13, Issue:20
| Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain. |
| AID458588 | Cytotoxicity against human MCF10A cells after 48 hrs by SRB assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach. |
| AID245952 | Half-maximal cytotoxic concentration in human foreskin fibroblast (HFF) cells | 2005 | Journal of medicinal chemistry, Apr-21, Volume: 48, Issue:8
| Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. |
| AID244635 | Ratio of Effective concentration to inhibit vaccinia virus plaque formation to that of half maximal cytotoxic concentration in human foreskin fibroblast (HFF) cells | 2005 | Journal of medicinal chemistry, Apr-21, Volume: 48, Issue:8
| Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. |
| AID246367 | Effective concentration required to inhibit vaccinia virus plaque formation in human foreskin fibroblast (HFF) cells | 2005 | Journal of medicinal chemistry, Apr-21, Volume: 48, Issue:8
| Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. |
| AID458585 | Cytotoxicity against human MDA-MB-468 cells after 48 hrs by SRB assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach. |
| AID757402 | Inhibition of Trypanosoma brucei rhodesain | 2013 | Journal of medicinal chemistry, Jul-25, Volume: 56, Issue:14
| Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis. |
| AID1368767 | Inhibition of human GSK-3beta at 10 uM using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE substrate peptide and [gamma-33P-ATP] incubated for 40 mins by scintillation counting method | 2018 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 28, Issue:2
| Discovery of new GSK-3β inhibitors through structure-based virtual screening. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |