bis(2-ethylhexyl) adipate : A diester resulting from the formal condensation of the carboxy groups of adipic acid with 2-ethylhexan-1-ol. It is used as a plasticiser in the preparation of various polymers. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
ID Source | ID |
---|---|
PubMed CID | 7641 |
CHEMBL ID | 1414950 |
CHEBI ID | 34675 |
SCHEMBL ID | 27423 |
MeSH ID | M0494748 |
Synonym |
---|
AC-15178 |
MLS002152897 , |
smr001224508 |
deha |
inchi=1/c22h42o4/c1-5-9-13-19(7-3)17-25-21(23)15-11-12-16-22(24)26-18-20(8-4)14-10-6-2/h19-20h,5-18h2,1-4h |
vestinol oa |
nsc-56775 |
sicol 250 |
monoplex doa |
plastomoll doa |
wickenol 158 |
wln: 4y2 & 1ov4vo1y4 & 2 |
di(2-ethylhexyl)adipate |
kodaflex doa |
flexol a 26 |
truflex doa |
nsc56775 |
adipol 2eh |
103-23-1 |
effomoll doa |
adipic acid, bis(2-ethylhexyl) ester |
witamol 320 |
bisoflex doa |
hexanedioic acid, bis(2-ethylhexyl) ester |
nci-c54386 |
diethylhexyl adipate |
bis(2-ethylhexyl) adipate |
di(2-ethylhexyl) adipate |
NCGC00091185-01 |
arlamol doa |
crodamol doa |
px-238 |
flexol plasticizer a-26 |
bis-(2-ethylhexyl)ester kyseliny adipove [czech] |
beha |
hexanedioic acid bis(2-ethylhexyl) ester |
effemoll doa |
ccris 236 |
brn 1803774 |
uniflex doa |
rucoflex plasticizer doa |
flexol plasticizer 10-a |
hsdb 343 |
ai3-28579 |
ergoplast addo |
bis(2-ethylhexyl) hexanedio ate |
dioctyl adipate (van) |
mollan s |
nsc 56775 |
bis(2-ethylhexyl)hexanedioate |
effomoll da |
staflex doa |
einecs 203-090-1 |
uss 700 |
adipic acid bis (2-ethylhexyl) ester |
jayflex doa 2 |
morflex 310 |
plasthall doa |
k 3220 |
sansocizer doa |
hatcol 2908 |
di-(2-ethylhexyl) adipate |
kemester 5652 |
reomol doa |
vistone a 10 |
keme ster 5652 |
lankroflex doa |
DOA , |
bis(2-ethylhexyl) adipate, >=99% |
bis(2-ethylhexyl) adipate, analytical standard |
bis(2-ethylhexyl) adipate, 99% |
NCGC00091185-02 |
bis(2-ethylhexyl) hexanedioate |
octyl adipate (van) |
NCIOPEN2_007625 |
di-2-ethylhexyl adipate |
A0163 |
adipic acid di(2-ethylhexyl) ester |
adipic acid di[2-ethylhexyl]ester |
NCGC00091185-03 |
NCGC00091185-04 |
dtxsid0020606 , |
NCGC00259780-01 |
tox21_202231 |
cas-103-23-1 |
NCGC00254473-01 |
dtxcid40606 |
tox21_300564 |
bis(2-ethylhexyl)adipate |
hexanedioic acid, 1,6-bis(2-ethylhexyl) ester |
bis-(2-ethylhexyl)ester kyseliny adipove |
ec 203-090-1 |
unii-mby1sl921l |
mby1sl921l , |
FT-0621915 |
AKOS015903805 |
di(2-ethylhexyl) adipate [iarc] |
bis(2-ethylhexyl)hexanedioate [hsdb] |
diethylhexyl adipate [inci] |
di-(2-ethylhexyl)adipate [mart.] |
SCHEMBL27423 |
CHEBI:34675 , |
adipic acid bis(2-ethylhexyl) ester |
cid_7641 |
bdbm74247 |
palatinol doa |
bis-(2-ethylhexyl)ester kyseliny adipove (czech) |
good-rite gp-223 |
adipic acid, di(2-ethylhexyl) ester |
monsanto doa |
CHEMBL1414950 |
1,6-bis(2-ethylhexyl) hexanedioate |
J-519866 |
J-000910 |
adipic acid di(2-ethylhexyl)ester |
mfcd00009496 |
bis(2-ethylhexyl) adipate, selectophore(tm), >=99.0% |
bis(2-ethylhexyl) adipate, >=97.0% (gc) |
adipic acid-bis-2-ethylhexylester |
adipic acid, bis-2-ethylhexyl ester |
adipic acid, bis-2-ethylhexyl ester 100 microg/ml in acetone |
hexanedioc acid, dioctyl ester |
witcizer 412 |
hexadioic acid, dioctyl ester |
doa plasticizer |
merrol doa |
flexol a26 |
i-2-ethylhexyl adipate |
jayflex doa |
DS-7125 |
Q412835 |
AMY40786 |
2072051-04-6 |
A855142 |
CS-W009768 |
Role | Description |
---|---|
plasticiser | Any compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers. |
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Class | Description |
---|---|
diester | A diester is a compound containing two ester groups. |
carboxylic ester | An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. |
dicarboxylic acids and O-substituted derivatives | A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 19.9526 | 0.0040 | 23.8416 | 100.0000 | AID485290 |
Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 56.2341 | 0.6310 | 35.7641 | 100.0000 | AID504339 |
RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 2.1690 | 0.0060 | 38.0041 | 19,952.5996 | AID1159523 |
AR protein | Homo sapiens (human) | Potency | 27.1672 | 0.0002 | 21.2231 | 8,912.5098 | AID1259243 |
thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 0.0794 | 0.0013 | 18.0743 | 39.8107 | AID926; AID938 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 33.7719 | 0.0030 | 41.6115 | 22,387.1992 | AID1159552; AID1159555 |
retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 30.9484 | 0.0008 | 17.5051 | 59.3239 | AID1159527; AID1159531 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 24.2128 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 0.3890 | 0.0002 | 29.3054 | 16,493.5996 | AID743075 |
bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 2.2387 | 0.7079 | 36.9043 | 89.1251 | AID504333 |
peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 24.5412 | 0.0010 | 19.4141 | 70.9645 | AID743094 |
serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 25.1189 | 0.7079 | 25.1119 | 41.2351 | AID485349 |
chromobox protein homolog 1 | Homo sapiens (human) | Potency | 56.2341 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.0200 | 0.0100 | 39.5371 | 1,122.0200 | AID588547 |
transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 77.0379 | 0.7943 | 21.2757 | 50.1187 | AID624246; AID651804 |
geminin | Homo sapiens (human) | Potency | 0.1859 | 0.0046 | 11.3741 | 33.4983 | AID624296; AID624297 |
cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 0.0316 | 10.2792 | 39.8107 | AID884; AID885 |
Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 5.3080 | 0.0266 | 22.4482 | 66.8242 | AID651802 |
Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1.0000 | 12.2248 | 31.6228 | AID885 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
ORF73 | Human gammaherpesvirus 8 | EC50 (µMol) | 75.0000 | 0.0600 | 8.1346 | 32.1400 | AID435023 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Process | via Protein(s) | Taxonomy |
---|---|---|
plasma membrane | Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) |
nucleus | Nuclear receptor ROR-gamma | Homo sapiens (human) |
nucleoplasm | Nuclear receptor ROR-gamma | Homo sapiens (human) |
nuclear body | Nuclear receptor ROR-gamma | Homo sapiens (human) |
chromatin | Nuclear receptor ROR-gamma | Homo sapiens (human) |
nucleus | Nuclear receptor ROR-gamma | Homo sapiens (human) |
plasma membrane | Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) |
plasma membrane | Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) |
[Information is prepared from geneontology information from the June-17-2024 release] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (32.23) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |